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Biomedical subjects

J S Wright

Publications and source records attributed to J S Wright.

At least 73 records · Page 4Linked to original sources

The peri-operative measurement of cardiac output in infancy by the thermodilution technique.

Cardiac output has been measured in infants by thermodilution during and after surgery. A method employing commerically available equipment has been developed. An animal model has been devised whereby right heart outputs of 210 ml to 2240 ml, measured by thermodilution, could be compared with left heart outputs measured by an aortic by-pass. The results of this study suggest that thermodilution is a simple, accurate method for measurement of cardiac output in infancy.

Age Factors↗

Some advantages of the membrane oxygenator for open-heart surgery.

The Lande'-Edwards oxygenator has been used for clinical perfusions on 283 patients. Among these patients we have encountered the full range of congenital and acquired defects and a variance in age from 1 day to adulthood. Data are presented concerning the means and methods of perfusion, the defects involved, and the results of treatment. A comparison has been made between two groups of 20 adults each, one group perfused with a bubble oxygenator (Bently) and the other with the Lande'-Edwards membrane lung. This study showed that platelet function is better preserved by the membrane lung, that hemolysis is less severe, and that postoperative bleeding is reduced. Indirect evidence has been accumulated to suggest that pulmonary, cerebral, and renal function is also better preserved when the membrane lung is employed.

Adolescent↗