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Biomedical subjects

J S Werry

Publications and source records attributed to J S Werry.

At least 37 records · Page 2Linked to original sources

Child psychiatric disorders: are they classifiable?

Classification of child (including adolescent) disorders is reviewed within six areas: requirements for a good taxonomy, current systems of classification for children, data-capture methods, reliability and validity, the link between child and adult disorders, and directions for future developments. While substantial progress has been made, there is a continuing need for comparisons of different systems, more systematic yet practicable data capture, proper psychometric analyses of criteria and categories, intensive studies of clinical validity, closer attention to the similarity of, and links between, child and adult categories, and better definition and targeting of those disorders with a serious outcome.

Child↗

Schizophrenia.

Schizophrenia occurring in childhood and adolescence has similar diagnostic, prognostic, and treatment ramifications as those noted with adult-onset schizophrenia. In assessing a child or adolescent suspected of having schizophrenia, care must be given to document DSM-III-R diagnostic criteria within the developmental framework of the patient's functioning, while thoroughly evaluating for other potentially confounding disorders or conditions. Antipsychotic therapy is the only specific treatment for schizophrenia, and should be a fundamental component with a multimodal treatment program that also addresses the psychological, social, and educational needs of the patient and his or her family. Strategies for medication management vary depending on several factors, including the stage of the disorder, noted or potential side effects, and the response of the patient to treatment, and need to be coordinated for the long term by a child or adolescent psychiatrist familiar with the diagnosis and treatment of schizophrenia in this age group.

Adolescent↗

Childhood and adolescent schizophrenic, bipolar, and schizoaffective disorders: a clinical and outcome study.

Fifty-nine child and adolescent psychotic patients (mean onset age 13.9, range 7-17, 83% 13 + years) had history and outcome studied using diagnoses confirmed at follow-up after 1 to 16 years (mean, 5 years). There were no differences in sex ratio, socioeconomic status, age of onset, and symptoms, but bipolar patients (N = 23) were often misdiagnosed as schizophrenic, had a better outcome, and a 50% homotypic family history. Schizophrenic subjects (N = 30) were more abnormal premorbidly, and only 17% were well at follow-up. Schizoaffective disorder was unreliable, infrequent, and more severe. Premorbid adjustment and IQ were the best predictors of outcome. Differences from the adult disorders were only quantitative. Careful follow-up of psychotic patients is needed to detect diagnostic errors.

Adolescent↗

Overanxious disorder: a review of its taxonomic properties.

The taxonomic properties of overanxious disorder are reviewed using the diagnostic criteria and other features listed in the DSM-III-R manual as a template. The data suggest that overanxious disorder is only a modestly reliable, distinct and valid taxon, and that adjustments to the diagnostic items and criteria and improved sources and methods of data capture are needed. Such changes should be on the basis of empirical data. Since these data are not yet extant, better psychometric-type studies are needed, coupled to assessments of validity. Recently, there has been a distinct increase in number and quality of studies. Although some adjustments are needed, to alter overanxious disorder too much in DSM-IV could make past studies of doubtful relevance and could force a fresh start instead of building on current knowledge.

Adolescent↗

Sensory integration and teacher-judged learning problems: a controlled intervention trial.

Seventy-four children from 21 schools referred because of teacher-perceived learning difficulties and prescreened for sensory integration (SI) deficits were given tests of SI, reading, vocabulary, perceptuo-motor function and motor development, and their teachers rated their classroom behaviour. The results showed that the children suffered primarily from attention deficit disorder without hyperactivity, and from mild deficits of SI. They were then divided into two groups matched approximately for sex, school and degree of SI deficits. One group received no treatment while the other was given about 13 weekly SI sessions, each of 1 h duration. All children were then reassessed on the same set of measures. There were significant improvements with time in both treated and untreated groups on most measures except classroom behaviour. Only one measure showed a treatment effect, though this one was most reflective of SI theory.

Attention Deficit Disorder with Hyperactivity↗

Behavior therapy with children and adolescents: a twenty-year overview.

A twenty-year overview of behavior therapy with children and adolescents is presented. The various techniques and their application to relevant major DSM-III-R categories are critically discussed. It is concluded that behavior therapy has made great progress and has proven applications in child and adolescent disorders but that its precise roles, comparative efficacy, and complementarity to other forms of psychotherapy and other treatments remain to be demonstrated. Much uncertainty stems from the relatively poor state of research in other forms of psychotherapy.

Adolescent↗

The ME syndrome.

Explore the source record for details and available documents.

Attitude of Health Personnel↗

Attention deficit, conduct, oppositional, and anxiety disorders in children: III. Laboratory differences.

Children aged 5-13 years with DSM-III diagnoses of Attention Deficit (ADDH), Anxiety, (ANX), or Conduct plus ADDH (HC) Disorder and matched normal controls were compared on a set of laboratory measures of impulsivity, arousal, motor performance, activity level, and cognition, and on behavior ratings during testing. While ANX patients did not differ from their controls, ADDH and HC patients did on Verbal IQ, most of the behavior ratings, and on about one-third of the test variables. ANX patients were about 1 year older, and more likely to be female, than ADDH and HC patients. When age, sex, and verbal IQ effects were partialed out, very few differences among the three diagnostic groups remained. The importance of precise control of such variables is emphasized and the impact of the failure to do so in past studies is discussed. The question is raised whether the deficit in verbal IQ is not so much a defect of matching as the essential feature of ADDH from which most of the other commonly reported cognitive symptoms stem.

Adolescent↗