Search PubMed⌕ Search

Biomedical subjects

J S Spratt

Publications and source records attributed to J S Spratt.

At least 19 recordsLinked to original sources
PubMed2000

Cancer of the anus.

Cancers of the anus, whether keratinizing squamous, nonkeratinizing, clear-cell, or melanoma, are infrequent neoplasms. Small keratinizing (<4 cm2) with no deep invasion can be controlled by local excision or laser ablation, but larger ones may be treated by chemoirradiation, restricting abdominoperineal resection to recurrences. Neither melanomas nor clear-cell cancers are curable, and local control is the surgical objective. Prophylactic groin dissection is not required but, for enlarged nodes or in the presence of a positive sentinel node biopsy, may be curative in many cases and palliative in all.

Abdomen↗
PubMed1999

Biological considerations with pelvic neoplasms.

The strategy of therapy for any neoplasm is determined to a significant degree by the biological characteristics of the neoplasm. The ones benefited most by surgical ablation are the cancers that grow locally but never metastasize. The second group is composed of neoplasms with exceedingly slow growth rates permitting long periods of symptom-free survival before recidivation. Many such cancers occur in pelvic structures requiring understanding of the nature of the cancers and then techniques necessary for their resection. The review provides an introduction to some of the relevant biological considerations.

Adenocarcinoma↗
PubMed1999

Exenterative pelvic surgery.

A review of the history, indications, basic technique, end results, and complications of exenterative surgery for pelvic neoplasms is provided. The authors discuss their broad personal experience with the operation. Much of this experience evolved from work at Barnes Hospital and the Ellis Fischel State Cancer Hospital. The techniques are applicable to advanced neoplasms of the cervix uteri, scrotum, urinary bladder, and other, less frequent neoplasms still confined to the pelvis.

Female↗