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Biomedical subjects

J S Shilling

Publications and source records attributed to J S Shilling.

30 records · Page 2Linked to original sources
PubMed1976

Vascular changes after retinal branch vein occlusion.

I have described the vascular changes after retinal branch vein occlusion and have shown progressive changes both in the large retinal vessels and in the capillary bed. The capillary reactions are comparable to those seen in central retinal vein occlusion. Retinal oedema due to capillary dilatation and leakage occurs in both conditions but, whereas this is generalized in central retinal vein occlusion, local changes occur in branch vein occlusion. Capillary closure also occurs in both conditions, but the neovascular response differs. In branch vein occlusion significant new vessel formation is restricted to the retina leading to recurrent vitreous haemorrhage. This contrasts with central retinal vein occlusion in which thrombotic glaucoma due to predominantly anterior segment neovascularization is the most serious cause of visual loss.

Fluorescein Angiography↗
PubMedDate not supplied

Assessment by fluorescein angiography of surgical treatment of occlusive carotid artery disease.

Fundus fluorescein angiography was performed in 10 cases of occlusive carotid artery disease at presentation and after surgery or medical treatment. An improvement in the microcirculation of the retina was observed in 4 cases after carotid endarterectomy and in 1 case after carotid endarterectomy and extracranial-intracranial bypass. Improvement was not observed in 2 cases after extracranial-intracranial bypass alone or in 3 cases in which surgical intervention was not undertaken. Our results suggest that carotid endarterectomy is a more effective procedure than extracranial-intracranial bypass in improving retinal perfusion when compromised by ipsilateral carotid obstruction.

Arterial Occlusive Diseases↗
PubMedDate not supplied

Factors predisposing to postoperative intraocular inflammation.

This prospective study of 123 patients undergoing cataract extraction determined the preoperative and surgical factors predisposing to an exaggerated postoperative inflammatory response. It is important to identify the patients at increased risk of complications requiring additional prophylaxis or more intensive postoperative care, particularly when selecting patients for day case surgery. Previous intraocular inflammation or surgery was the factor most strongly associated with marked inflammation on the first postoperative day (p < 0.01, compared to uncomplicated patients). As a result, patients stayed in hospital an average of one day longer (p < 0.001) and required significantly more steroid drops (p < 0.001). Other factors of significance, but reducing importance were: difficult surgery, non-caucasian race and brown irides. Amongst uncomplicated patients, the difficulty of surgery was most significantly related to a high inflammation score (p < 0.01). Non-caucasian patients stayed in hospital significantly longer than their caucasian counterparts (p < 0.05), and required more steroid drops (p < 0.001). Of caucasian patients, those with brown irides were inpatients for significantly longer than those with blue or hazel (p < 0.05). No other factors studied significantly altered postoperative inflammation: neither the presence of diabetes, nor the technique of cataract extraction.

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