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Biomedical subjects

J S Clark

Publications and source records attributed to J S Clark.

67 records · Page 4Linked to original sources

Safety and efficacy of continuous flush systems for arterial and pulmonary artery catheters.

Air embolism and static pressure errors have been attributed to continuous infusion systems. Experiments show that the primary source of air bubbles in such a system is the drip chamber. A drip chamber that minimizes this problem was tested and is recommended. Pressure errors due to the flush system are shown to be clinically insignificant. Fast flushing through a central arterial catheter is shown to be a minimal hazard.

Arteries↗

Osteodentin formation in continuously erupting teeth of guinea pigs.

Osteodentin formation in guinea pig teeth was studied using in vivo microscopic and histologic techniques. The coronal half of both incisors and molars contained varying amounts of osteodentin. Within the osteodentin, narrow canals that contained pulp tissue were observed. Serial histologic sections demonstrated that these canals opened to the occlusal surface thereby exposing the pulp to the oral cavity.

Animals↗

Use of the Bard Memotherm self-expanding metal stent in the palliation of colonic obstruction.

BACKGROUND: Self-expanding metal stents (SEMS) are a recognized means of palliating large bowel obstruction due to colonic neoplasia. The literature mainly relates to the use of modified esophageal stents (expanded diameter, 18-22 mm) in the colorectum. Stent migration has been a common complication and may be related to expanded stent diameter. This series reports our experience with the Memotherm Colorectal SEMS (expanded diameter, 25-30 mm). METHODS: Prospective data were collected from February 1999 to September 2000. Sixteen patients (age range = 61-99 years) were considered for the Memotherm Colorectal SEMS. Stents were inserted radiologically under fluoroscopic control. Outcome was classified as a technical success (stent in correct position and expanded) and a clinical success (colon decompressed, symptoms relieved, and bowels working). RESULTS: Thirteen cases (81%) underwent successful SEMS placement. These were technically and clinically successful. Two cases required insertion of two overlapping stents to traverse long strictures. Three unsuccessful cases were emergency presentations in which a guidewire could not be passed across the lesion. Two of these were due to benign strictures and the third to extrinsic compression by ovarian carcinoma. CONCLUSION: In our experience, the Memotherm Colorectal SEMS was easy to use, was effective in the palliation of obstructing colorectal carcinoma, and appeared to reduce the risk of stent migration.

Aged↗

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Adaptation, Psychological↗