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Biomedical subjects

J Ryzko

Publications and source records attributed to J Ryzko.

At least 19 recordsLinked to original sources
PubMed2004

Beneficial effect of liver transplantation on bone mineral density in small infants with cholestasis.

Reports of bone mineral density in children after liver transplantation are few. Eleven cholestatic children were analyzed before and 6 months after liver transplantation. No changes in serum levels of calcium, alkaline phosphates, or 25OHD were observed before versus after LTx. The serum levels of phosphorus and 1-25(OH)2D3 as well as total bone mass density and Cole index were significantly increased after liver transplantation.

Bone Density↗
PubMed2003

The past and present of the Polish paediatric gastroenterology, hepatology and nutrition.

Gastroenterology has emerged from paediatrics as a separate discipline after 1978, due to the development of basic sciences, i.e., biochemistry, immunology, pathomorphology and introduction of miniaturized endoscopic and radiological equipment. This paper describes the most significant achievements in the areas of gastroenterology, hepatology, and nutrition in children in particular medical centres in Poland. It also discusses the role of the Polish Society for Paediatric Gastroenterology, Hepatology and Nutrition, the role of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), and the role of other Scientific Societies and Foundations supporting the development of science and education. The emphasis has been placed upon utilitarian research and education with regard to the management of children with gastrointestinal and hepatic disease.

Child↗
PubMed1995

[Evaluation of nonspecific inflammatory bowel disease in children using disease activity scoring systems].

Scoring systems for assessment of clinical activity of IBD were used to evaluate 62 children with IBD (14 with CD, 35 with CU and 13 with CNS). The PCDAI system was most effective in children with CD. In children with CU, both modified Truelove-Witts and Rachmilewitz indexes are equally effective, however use of the Truelove-Witts scale is simpler. The Rachmilewitz scale is better in distinguishing between UC and CNS.

Adolescent↗
PubMed1995

[Changes in the gastrointestinal system of children with inflammatory systemic connective tissue diseases].

Functional and morphological changes of the gastrointestinal system were assessed in patients suffering from juvenile chronic arthritis, juvenile systemic erythematosus and juvenile systemic scleroderma. The results of endoscopic investigation of the gastrointestinal tract showed inflammatory changes and cardiac and pylorus atony. Ultrasonography results suggested hepatic and pancreatic inflammatory changes, steatosis and/or amyloidosis. The above-mentioned changes were confirmed by morphological investigation (biopsy and/or autopsy). The results of the capacity tests performed in JCA (systemic form) patients revealed an impairment of liver detoxication function, and pancreas and bowel functional capacity as well. Additionally, intolerance against lactose, casein and alpha- and beta-lactoglobulin was found in most of the patients. Some symptoms of malnutrition were observed in all of them. Such factors as underlying disease severity, adverse drug effects, environmental factors (infections, nutrition) were taken into consideration as probable causes of the gastrointestinal system damage.

Adolescent↗
PubMed1995

[Giant-cell hepatitis in a 10-year-old boy].

In this paper we present a 10-year-boy with viral giant-cell hepatitis with a immune component. We observed clinical, biochemical and histological improvement after treatment.

Bilirubin↗
PubMed1993

Internal organ involvement in juvenile connective tissue disease.

Using noninvasive investigative techniques, cardiac, pulmonary and gastrointestinal abnormalities were found in patients with all types of connective tissue diseases. Impedance rheography suggested impaired myocardial function. Abnormalities of pulmonary function included a decrease in diffusing lung capacity for CO (DL) values followed by restrictive ventilatory defects and mild alveolar hyperventilation. The results of endoscopic investigation of the gastrointestinal tract showed inflammatory changes. Ultrasonography revealed dyskinesis of the ducts of the gallbladder and some hepatic and pancreatic structural changes.

Child↗
PubMed1992

[Recurrent abdominal pain in children].

In the paper the results are presented of an analysis of the causes of recurrent abdominal pain in 294 children hospitalized at the Gastroenterology Department, Childrens Health Centre, and the accepted diagnostic programme is evaluated. The children were referred to the CHC, as a rule with a suggestion of organic causes of recurrent abdominal pain. On the basis of carried out examinations the following was diagnosed: in 111 children organic causes (37.8% of the studied group), in 94 children recurrent abdominal pain of functional aetiology (32%), in 53 children psychological background (18%), and in 36 children mixed organic and functional background. These proportions between those groups is the result of the selection carried out at earlier stages of the diagnostic process. In the paper, the correctness and validity of the accepted diagnostic programme are also demonstrated.

Abdominal Pain↗
PubMed1992

[Clinical-morphologic analysis of children dying of intoxication with Amanita phalloides].

The results were subjected to analysis of 23 autopsies carried out in children dying of intoxication with Amanita phalloides. The correlation of the pathomorphological findings with the clinical picture and biochemical pattern was evaluated. The morphological changes were also presented in organs other than the liver which is recognized as the target organ for Amanita phalloides toxins.

Adolescent↗
PubMed1989

Endogenous, cutaneous vitamin D synthesis stimulation as an effective way of improving the vitamin D status in children with hepatobiliary malfunctions.

Repetitive (5 days) ultraviolet treatment was used to improve vitamin D status of 26 pediatric patients suffering from different hepatobiliary disorders. The treatment resulted in a significant improvement of patients' vitamin D and 25-hydroxyvitamin D levels regardless of their disease and other factors such as increased blood bilirubin content or jaundice. Presence of a dependence between the increase in 25-hydroxyvitamin D concentrations after treatment and its original levels was confirmed.

Adolescent↗
PubMed1989

[Fiber-optic endoscopy of the lower gastrointestinal tract in children].

Between 1978 and 1985 565 lower gastrointestinal endoscopies were performed in children. In 221 cases the cause of rectal bleeding was explored, in 227 the suspicion of colitis and in 25 of polyposis was verified. To evaluate the results of treatment (polypectomy, surgical procedures and medical therapy in inflammatory bowel disease) 121 examinations were done. With increasing experience the complete colonoscopy was performed more often. In 1985 coecum and ileum terminale was reached in almost all children in whom it was needed (75% of all examinations). The inflammatory changes were revealed on 230 occasions. In 78 cases colon polyps and in 27 vascular changes were found. The most common cause rectal bleeding were colon polyps (66 cases) and inflammatory changes (554 cases). Less common were vascular changes (10 cases). 32% false negative and 16% false positive results of colonoscopy in diagnosis colitis were obtained when the results of visual findings were compared with histopathological findings. Colonoscopy performed by an experienced colonoscopist rather avoiding general anesthesia is a safe and useful procedure in diagnosing lower gastrointestinal tract diseases in children. The evaluation of colitis should be based on visual findings with biopsy confirmation.

Adolescent↗
PubMed1989

[Changes in vitamin D metabolism in children following partial intestinal resection].

Six children (five after partial intestinal resection, one after colectomy) were studied with respect to absorption and metabolism of vitamin D. The results showed decreased 25-OH-D3 serum concentrations below 20 ng/ml (in two patients even below 10 ng/ml), possibly due to disturbed enterohepatic circulation of vitamin D metabolites.

Adolescent↗