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Biomedical subjects

J Ruzicka

Publications and source records attributed to J Ruzicka.

46 records · Page 3Linked to original sources

Encephalopathy, peripheral neuropathy, dysautonomia, myasthenia gravis, malignant thymoma, and antiacetylcholine receptor antibodies in the CSF.

A 54-year-old man suffered from multiple neurologic disturbances (polyneuropathy, encephalopathy, dysautonomia) associated with myasthenia gravis and malignant thymoma. No morphological signs of inflammation were present in the brain and peripheral nerves. Antiacetylcholine receptor antibodies were present in the brain and peripheral nerves. Antiacetylcholine receptor antibodies were present in serum and in cerebrospinal fluid. The association of thymoma, myasthenia gravis, multiple neurologic syndromes, and antiacetylcholine receptor antibodies in serum and cerebrospinal fluid has not been reported as yet. We suggest that this clinical picture is related to a generalized cholinergic dysfunction.

Atrophy↗

Morphology of adenocarcinoma in situ of the uterine cervix: a study of 14 cases.

Fourteen cases of adenocarcinoma in situ (ACIS) of the cervix in patients 30 to 52 years old were studied. In its pure form (four cases, ACIS was discovered cytologically, but when associated with a squamous abnormality (ten cases), it was found histologically. Two different types of ACIS were distinguished both histologically and cytologically. The first type, which was similar to the common form reported in the medical literature, predominated in 12 cases, and consisted of cells with hyperchromatic and pseudo-stratified nuclei. The second type, which predominated in two cases, displayed a conspicuous structural disorder with unequal, larger, and often clear nuclei containing enlarged nucleoli.

Adenocarcinoma↗

Flow injection analysis using ion-sensitive field effect transistors. A model system for discrete assays and continuous in vitro monitoring of pH and pCa.

A miniaturized flow injection system yields an instant readout and requires microlitre volumes of sample and reagent solutions. Using electrode measurement as an example it is shown that the difference between discrete assays and continuous monitoring becomes so small that the same apparatus will eventually perform both functions.

Calcium↗