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Biomedical subjects

J Ruskin

Publications and source records attributed to J Ruskin.

71 records · Page 4Linked to original sources
PubMed1968

Immunity and intracellular infection: resistance to bacteria in mice infected with a protozoan.

Mice infected with the intracellular parasite Toxoplasma gondii for periods of as long as 7 months were resistant to challenge with numbers of Listeria monocytogenes and Salmonella typhimurium that were uniformly lethal to normal mice. This resistance did not appear to depend on the strain of toxoplasma employed or the route of inoculation of either toxoplasma or bacteria. Onset of immunity to listeria was demonstrable as early as 1 to 2 days after infection with toxoplasma. Resistance to toxoplasma was not demonstrable in mice immune to listeria. Interferon did not appear to be a mediator of the immunity observed in toxoplasma-infected mice.

Animals↗
PubMedDate not supplied

Cryothermal ablation: mechanism of tissue injury and current experience in the treatment of tachyarrhythmias.

Cryosurgery has been an integral part of the surgical management of cardiac arrhythmias since the late 1970s. With the recent development of intravenous cryocatheters, the use of cryothermy in the treatment of cardiac arrhythmias will increase in the near future. The following discussion includes a detailed consideration of the mode of tissue injury associated with cryothermy and a comprehensive review of cryosurgery in the management of a variety of cardiac arrhythmias. Cryosurgical management of supraventricular and ventricular tachycardias has proven to be both safe and effective. Cryothermal tissue injury is distinguished from hyperthermic injury by the preservation of basic underlying tissue architecture and minimal thrombus formation. Such differences will be particularly important in settings requiring extensive lesion formation, such as catheter-based maze procedures for the treatment of atrial fibrillation.

Atrial Fibrillation↗
PubMedDate not supplied

[Echocardiographic diagnosis of valvular vegetations. Study of a case].

A case of a 23 year old patient with clinical manifestations of subacute bacterial endocarditis is presented, proven during the surgical treatment, in which it was possible to establish the diagnoses of a vegetation of the mitral valve through echocardiography. The echocardiographic changes produced by vegetations are analyzed and the technical defects which may lead to interpretation mistakes. It is concluded, that this non-ivasive method is of very usefull diagnozing the establishment of vegetations on the cardiac valves.

Adult↗
PubMedDate not supplied

Osseointegration of titanium implants in bone regenerated in membrane-protected defects: a histologic study in the canine mandible.

In the present histologic study of the mandibles of five foxhounds, 15 nonsubmerged titanium implants were placed in bone regenerated in extended membrane-protected defects during a 6-month healing period. The clinical and radiographic evaluation demonstrated that all 15 implants achieved functional ankylosis within 3 months following implant placement. Subsequently, eight implants were restored with fixed partial dentures and were functionally loaded for 6 months, and seven implants were left unrestored. At the completion of the study, the histologic analysis demonstrated osseointegration with direct bone-to-implant contact for all 15 implants. Therefore, it can be concluded that bone regenerated in membrane-protected defects responds to implant placement like nonregenerated bone, and that this bone is capable of bearing and sustaining functional load. The histologic comparison of restored and unrestored sites demonstrated no apparent differences concerning bone remodeling activities. Furthermore, control sites without implant placement demonstrated bone atrophy underneath the membranes with a thin cortical layer and sparse bone trabeculae. Thus, it can also be concluded that the placement of an implant into regenerated bone stimulated bone maturation and bone remodeling, whereas implant loading did not influence bone remodeling in the present study model.

Alveolar Bone Loss↗