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Biomedical subjects

J Ruiz-Gómez

Publications and source records attributed to J Ruiz-Gómez.

At least 19 recordsLinked to original sources

Rotavirus. I. Hemagglutination and complement fixation inhibitor antibodies in individuals of Mexico city.

Hemagglutination inhibiting antibodies were studied in 1,278 sera of individuals of different ages in Mexico City representative of four different socioeconomic levels. It was found that 1,261 (98.7 per cent) had antibodies against the Nebraska strain (calf rotavirus). An unusual finding was that more than 95 per cent of children from one to four years of age, had antibodies. For this reason five year old children were studied utilizing two viral strains as antigens in hemagglutination inhibition tests. It was found that in 918 sera, 821 (89.4 per cent) had antibodies against SA-11 samples (monkey rotavirus); percentage increased from 87.2 per cent in neonates to 97.5 percent in children from four to five years of age. A similar phenomenon was observed when Nebraska strain hemagglutinin was utilized. Also complement fixation antibodies against SA-11 strain in 583 sera were studied finding that 260 (44.6 per cent) had antibodies. Utilization of this technique showed that seropositivity percentage decreased from 47.6 per cent in the neonate group to 14.5 per cent in the one ot three month old children increasing progressively until reaching 65.1 per cent in children three to four years of age. These results show that rotavirus infection takes place at early ages, as has been confirmed by other authors that have used electron microscopy techniques, RNA electrophoresis, etc., regardless of the presence of transplacental antibodies.

Adolescent↗

Rotavirus. II. Viruses associated with acute gastroenteritis in children.

Rotavirus was investigated in the feces of 232 children under five years of age with acute infectious gastroenteritis by means of viral RNA electrophoretic technique. 15.1 per cent of cases were positive and no predominance was observed regarding age or seasonal period. Approximately 50 per cent corresponded to one of the two rotavirus types, byt type 2 (2 L) was predominant in the first six months of the year and type 1 (2 S) in the other six. Results are consistent with those obtained by other authors for it is considered that approximately 20 per cent of acute diarrheas during infancy are caused by viral agents.

Acute Disease↗

Serum epidemiology of eastern, western and Venezuelan equine encephalitides in Mexico.

The presence of HI antibodies for the Eastern, Western and Venezuelan equine encephalitis was investigated in 16,405 human sera collected in 47 communities in the Mexican Republic. It was found that there is a high percentage of individuals who have antibodies against Venezuelan equine encephalitis. In turn, it was discovered that persons with Western equine encephalitis virus antibodies live in the northwestern states of the country. Very few cases with Eastern equine encephalitis antibodies were detected.

Adolescent↗

[Precipitation antibodies against poliovirus in patients with poliomyelitis].

Sera from 26 children bearing poliomyelitis caused by virus tipe I and from 47 cases with paralysis of different etiology (non-poliomyelitic) were tested against antigen of poliovirus types I, II and III with an agar-immunoprecipitation reaction. All sera with neutralizing antibodies with titres of 1:1250 gave positive results in immunodifusion tests. The percentage of positiveness decrease with lower titres. No false positive reactions were found. Immunodiffusion test with antigens of poliovirus were positive in 100% of sera from patients with poliomyelitis and only in 30% in sera from patients with non polio paralysis.

Antigens, Viral↗

[Depression and Herpex simplex infections].

It has been mentioned that herpes simplex antibodies are increased in depressed patients. In the present study, serums from 21 patients with reactive depressions, nine with psychotic depression, 33 schizophrenic and 15 normal controls were studied, and herpes simplex antibodies were measured. Neither was statistically significant difference found between any of the groups nor could antibody titres be correlated with severity of depression measured by a psychiatric rating scale. The authors review the pertinent literature, and state that although antibody tires do not correlated with psychiatric diagnosis, there still exists the possibility that latent brain viral infections might trigger depressive episodes in some cases.

Adolescent↗