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Biomedical subjects

J Rudnik

Publications and source records attributed to J Rudnik.

At least 37 records · Page 2Linked to original sources
PubMed1981

The evaluation of immune status in children with the past history of obstructive bronchitis.

Selected parametres reflecting cellular and humoral immunity were analyzed in 98, 10 year-old children, who had been hospitalized during first 2 years of life because of bronchitis. In this group, 46 children suffered from obstructive bronchitis and 52 from other types of bronchitis. Serum immunoglobulins, complement components, and antiproteolytic factor levels, T and B lymphocytes counts, leukocyte migration inhibition, and skin tests to PHA and Polyvaccine were compared and analyzed in relation to bronchial obstruction and allergic symptoms in early childhood. The results obtained did not show any significant difference when the group with obstructive type of bronchitis was compared to the rest of children studied. Some differences (increase of the percentage of EAC-FRC and decrease of the levels of the antiproteolytic factors) were noted in relation to allergic symptoms.

Asthma↗
PubMed1981

Lung function of children with history of obstructive bronchitis in their infancy.

A group of 98 children admitted to the hospital in the first 2 years of life with diagnosis of obstructive bronchitis was reexamined at 10 years of age. The examination included complexed lung function measurements. No important functional abnormalities were found in relation to passed obstructive bronchitis, features of allergy, frequency of attacks of the disease in the past, and bronchial reactivity to histamine. In the small group of children with diagnosis of bronchial asthma in the meantime made, the results of examination were most frequently abnormal but did not coincide with the previous diagnosis. They indicated rather nonhomogeneity of ventilation, characteristic for peripheral lung abnormalities.

Bronchitis↗
PubMed1979

Proteins in bronchial secretion of children with chronic pulmonary diseases. I. Relation to clinical diagnosis.

Bronchial secretions from 207 children suffering from various pulmonary diseases and from 15 healthy controls were tested concentration of IgA, IgG, lactoferrin and lysozyme. The results obtained suggest that in many cases of chronic lung diseases in children the levels of lactoferrin and immunoglobulins, especially secretory IgA, are very low. In severe infections (cystic fibrosis, bronchiectases) significant increase of IgG concentration was observed.

Adolescent↗
PubMed1978

Activity of serum inhibitory proteases in bronchial secretions from children with various chronic non-specific respiratory diseases.

In a group of 223 children with various chronic, non-specific respiratory diseases, the levels of serum inhibitory proteolytic enzymes in bronchial secretions was measured. Activity of inhibitory proteolytic enzymes was analyzed according to the nature of bronchial lesions observed at bronchoscopy and character and cellular composition of bronchial secretion. Statistically significant increase of the mean inhibitory value in comparison to values in the control group, was found in children with recurrent bronchitis (a-1-AT), cystic fibrosis (a-1-AT and a-1-X), chronic bronchitis (a-1-X), bronchiectases (a-1-X) and in children with obstructive bronchitis (a-2-M).

Bronchi↗