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Biomedical subjects

J Rudnicki

Publications and source records attributed to J Rudnicki.

17 recordsLinked to original sources
PubMed2005

Tumour-like inflammatory abdominal conditions in children.

The presence of a tumour, poor general condition, features of anaemia, increased erythrocyte sedimentation rates and imaging suggesting malignancy were the common features in 4 different tumour-like abdominal conditions that are extremely rare in childhood. These conditions included: extensive retroperitoneal tumour with rib involvement that turned out to be an inflammatory lesion caused by Actinomyces in a 12-year-old girl; multi-loculated tumour of the mesentery/ovary caused by mesenteric lymphadenopathy in the course of a Salmonella enteritidis infection in a 2.5-year-old girl; tumour of the VII - VIII hepatic segments that turned out to be the focus of granuloma in the course of lambliasis in a 5.5-year-old boy with a history of purulent neck lymphadenopathy and a final suspicion of immunocompromise; and a multi-loculated tumour of the small pelvis and inguinal area that turned out to be an abscess of the iliopsoas muscle in a 16-year-old boy. Apart from the imaging, the lesions required cytological examination of the material harvested by fine-needle biopsies (liver tumour) or histopathological investigations (retroperitoneal tumour, mesenteric/ovarian tumour, liver tumour and--on second surgery--the pelvic tumour) and/or bacteriological examination (all cases), serological examination (liver tumour and mesenteric/ovarian tumour), protozoal investigation (liver tumour), and measurement of AFP levels (mesenteric/ovarian tumour). Surgical treatment (retroperitoneal tumour, mesenteric/ovarian tumour and tumour of the small pelvis) and guided antibiotic therapy (all cases including 15 weeks of antibiotics in the first case) allowed complete recovery in 3 patients (actinomycosis, mesenteric lymphadenopathy, abscess of the iliopsoas muscle). Antibiotic and antiprotozoal therapy cured the granulomatous hepatitis; however this patient tended to develop severe right-sided pleural/pulmonary changes (the child was referred for further diagnosis with suspicion of immunocompromise).

Actinomycosis↗
PubMed2001

The myoelectric activity of ileum in fasted and fed young pigs.

To precise the character of myoelectric activity of distal small intestine, in 8 young pigs 1 bipolar electrode was attached at the serosal side of the jejunum and 7 electrodes were sutured at terminal ileum. After the recovery, the animals were fed twice daily during at least 2 weeks and were fasted 24 h before each experiment. Myoelectric activity was recorded with electroencephalograph throughout the experiment lasting 3-5 h. After control recording the standard food was given during the end of ileal phase 1 of migrating myoelectric complex (MMC) and registration of myoelectric activity was continued. Ileal propagated or non-propagated minute rhythm was observed in 64% of the experiments performed, during phase 2b of MMC. In most animals studied, the long isolated spike burst series lasting 1-6 min and short isolated spike burst series lasting 15-25 s were observed. Feeding induced myoelectric activity in the jejunum usually after 1-2 min and, in the ileum, during most episodes, after 2-9 min, for 4-10 min. During and after feeding, the short-lasting "transient fed pattern" was observed. Mean propagation velocity of phase 3 MMC was 4.4 +/- 0.8 and 8.1 +/- 0.6 cm/min (mean +/- S.E.M., p > 0.05) before and after feeding, respectively. Phase 3 MMC was preceded by 2-3 spike burst series lasting 40-70 s each before feeding and 1-3 min after feeding. Single propagated spike bursts arrived more frequently after feeding. Two types of minute rhythm, propagated and stationary, were observed. Giant spike bursts, propagated contractions and ultrarapid spike rushes were recorded occasionally. In conclusion, the myoelectric activity of terminal ileum in swine is eventful, exhibits wide range of irregularity and its response to feeding is relatively weak and delayed as compared to the upper small intestine.

Animals↗
PubMed1998

Prevalence and forms of congenital anomalies in twins born in Pomeranian District during the period from 1.07.1997 to 31.12.1998. Polish Register of Congenital Anomalies.

The authors have analysed the frequency and structure of congenital anomalies in children born in the Pomeranian district in the period from 01.07.1997 to 31.12.1998. Among a total of 28.361 births in that area, 748 (2.64%) were affected by congenital anomalies. Among 28.361 births, 620 (2.18%) were from multiple pregnancies. 23 (3.71%) among births from multiple pregnancies were affected by congenital malformations. The prevalence rate of inborn anomalies in births from multiple pregnancy in our area were higher (3.71%) in comparison to births from singleton pregnancy (2.61%). It implies that children born from multiple pregnancy are at higher risk of developing congenital anomalies.

Congenital Abnormalities↗
PubMed1998

[A case report of rubella embryopathy in pregnancy complicated by placental insufficiency].

This is a case report of sever rubella empryopathy confirmed by IgM and IgG titers estimation in newborn blood. This pregnancy was complicated by prolonged placenta insufficiency (oligohyramnions and IUGR). The cesarian section was done in 35 weeks of pregnancy. The newborn died in 9 days after delivery. Cause of death was sepsis, vitium cordis congenitum and respiratory insufficiency.

Adult↗
PubMed1995

[Evaluation of ambroxol given prenatally and postnatally on gas exchange in the newborn with respiratory distress syndrome].

160 newborns were observed to compare the influence of combine treatment with ambroxol (Lasolvan-Boehringer Ingelheim) (antenatal and postnatal) versus postnatal administration of this drug on gas exchange and reduction of ventilatory settings in newborns with RDS. In 53% of cases the preparation was given both: pre- and postnatal and 47% of newborns were treated only postnatal. The results of stimulation of lung maturity "before and after" versus "after" delivery were better in the first group, however in some parameters we did not found statistical differences.

Ambroxol↗
PubMed1995

[Comparison of mortality and morbidity in newborns treated with ambroxol prenatally and postnatally].

The effect of Ambroksol given pre- and postnatal on infant mortality and morbidity was performed. In particular we found a statistically significant differences in reduction of mortality in the group A treated with Ambroksol pre- and postnatal vs. group B treated only postnatal. The other parameters of morbidity had no significantly importance but sepsis, which was more often diagnosed in group A than in group B (17.5% vs. 11.1%). We connect this fact with higher frequency of PROM in the group A.

Ambroxol↗
PubMed1982

Adenoid basal cell carcinoma of the vulva.

Two cases of a subtype of basal cell carcinoma--the adenoid basal cell type--occurring in the vulva, are described. These lesions are frequently misdiagnosed as adenoid cystic carcinomas of the Bartholin's gland because of their histologic appearance. Their characteristic presentation, histology, and prognosis warrant their differentiation.

Aged↗
PubMedDate not supplied

[Bacteriophage therapy in the treatment of recurrent subphrenic and subhepatic abscess with jejunal fistula after stomach resection].

The case of recurrent subphrenic abscess with the jejunal fistula after stomach resection in 41-years old male is presented. In microbiological examination E. coli antibiotic-resisted was discovered. The bacteriophages were prepared and administered to the patient. The operation was performed without any antibiotics. During the whole stay at hospital the patient had got bacteriophages. He left the hospital in 33rd day of stay without any abscesses.

Adult↗