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Biomedical subjects

J Rud

Publications and source records attributed to J Rud.

At least 19 recordsLinked to original sources
PubMed2001

Periapical healing of mandibular molars after root-end sealing with dentine-bonded composite.

AIM: The purpose was to present the frequency of periapical healing in first and second/third mandibular molars, after root-end resections sealed with a dentine-bonded resin composite. METHODOLOGY: Root-end sealing of resected mandibular molar roots was made with dentine-bonded composite (Gluma-Retroplast) as a cover on the entire slightly hollowed root-end, in an attempt to prevent leakage. RESULTS: Out of the 834 roots recalled between 6 months and 12.5 years postoperatively, 92% showed complete apical healing, 1% uncertain healing and 7% exhibited failure. The healing result of 681 first molar roots was not significantly different (P = 0.21) from that of 153 second/third molar roots, and there was no significant difference in healing between mesial and distal roots (P = 0.32 for first molars, P = 0.86 for second/third molars) or amongst six age groups (P = 0.94). In the patient group: 71-89 years, 36 roots showed an average of 97% with complete healing. Out of 25 failures who were retreated surgically, 80% showed complete healing when examined subsequently. CONCLUSION: Root-end sealing of mandibular molars with dentine-bonded resin composite is a promising technique giving 92% complete healing in cases examined between 6 months and 12 years postoperatively.

Adolescent↗
PubMed1998

Surgical endodontics of upper molars: relation to the maxillary sinus and operation in acute state of infection.

Findings in 200 cases of root resection of first maxillary molars showed perforation to the sinus in half of the cases. In 42% of the cases, the first maxillary molar had root resection performed in a subacute or acute state of infection. Only two cases developed postoperative sinusitis. Antibiotic treatment was indicated preoperatively in 3% and postoperatively in 5%. Postoperative symptoms, such as pain and swelling, were usually moderate, possibly because of a nontraumatizing operation technique, a careful removal of infected tissue, and a good drainage by loose suturing.

Acute Disease↗
PubMed1998

Retrograde sealing of accidental root perforations with dentin-bonded composite resin.

Surgical treatment was performed on 100 iatrogen perforations, of which 94 showed radiolucency of bone adjacent to the perforation and 83 presence of an exposed post. The perforations were in all cases sealed with a resin composite (Retroplast) bonded to adjacent root dentin with a dentin bonding agent (Gluma). Cases were examined after approximately 1 yr (first recall) and, if necessary after 1 1/2 to 11 yr (mean: 4.1 yr) (latest recall). It was observed that the presence or absence of bone on the root between the perforation and cervix at the time of operation had no significant effect on the healing result, and that the radiographic classification "partial" healing with a border of cortical bone or a lamina dura often remained unchanged for many years. At latest recall, the healing result of 65 teeth originally having root perforation elsewhere than at the furcation was: 71% complete, 11% partial, 3% uncertain, and 15% failure. This is significantly different from the healing result of 27 molar teeth originally having perforation at the furcation: 30% complete, 41% partial, 11% uncertain, and 18% failure.

Adult↗
PubMed1997

Effect of root canal contents on healing of teeth with dentin-bonded resin composite retrograde seal.

Healing results were compared among 551 infected roots apically sealed with a dentin-bonded resin composite (Gluma-Retroplast). These roots contained either 1) root filling to apex after resection, 2) insufficient root filling, or 3) empty root canals with necrotic pulp remnants. At 2- to 4-yr follow-up, complete bone healing was found to be 92%, 85%, and 81% in groups 1, 2, and 3, respectively. The results from groups 1 and 3 were significantly different, and the results from group 2 did not differ significantly from that of groups 1 or 3. Reasons for "Failures" were found to be mainly loose filling or uncovered canal. After 21 roots classified as "Failures" were reoperated, 76% of these showed "Complete Healing" after 1 yr.

Adult↗
PubMed1996

Retrograde root filling with dentin-bonded modified resin composite.

A retrograde root-end cover with a special resin composite (Retroplast) combined with the dentin bonding agent Gluma (Bayer AG) has been used since 1984 by the authors. Its content of silver, added to promote radiopacity, has been found to lower the working time and storage stability of the composite and might cause discolorations. Since 1990, silver has therefore been replaced with ytterbium trifluoride, which eliminates these side effects. The purpose of this study was to compare the clinical results obtained with these two resin composites and to evaluate the healing results after several years in function. Apical fillings (351) with the modified Retroplast showed the following radiographic healing pattern 1 yr after surgery: 80% complete healing, 2% scar tissue, 12% uncertain healing, and 6% failure. No significant difference in this healing pattern was found, compared with that obtained with the silver-containing Retroplast. Cases with ytterbium trifluoride classified as scar tissue and uncertain healing at 1 yr when examined at 2 to 4 yr postoperatively showed 89% complete healing. 0% scar tissue, 1% uncertain healing, and 9% failure. This result is significantly different from that obtained 1 yr after surgery. Based on calculations, it was predicted that with time 90% will become complete healing, whereas 10% will become failure.

Bisphenol A-Glycidyl Methacrylate↗
PubMed1996

Long-term evaluation of retrograde root filling with dentin-bonded resin composite.

The purpose of this study was to investigate the long-term stability of apical retrograde root fillings using a dentin-bonded resin composite. Radiographs were used to establish the degree of healing around the apically filled roots. Patients examined were those who had previously showed complete healing 1 yr after surgery. Thirty-three of the first 34 consecutively placed resin composite apical fillings performed since the introduction of this method in 1984 were examined. Six of these fillings were examined 8 yr after surgery, and 27 of these fillings were examined 9 yr after surgery. Only one patient showed recurrence of periapical inflammation 8 yr after operation, probably caused by a root fracture. It was concluded that the bond established between dentin and the resin composite was stable during the observation period, and that the filling material had not been harmful to the surrounding tissues. If complete bone healing has been observed, it could be expected to remain stable, unless new factors, such as root fracture, occurred.

Adolescent↗
PubMed1993

Periodontal tissue regeneration including cementogenesis adjacent to dentin-bonded retrograde composite fillings in humans.

The roots of two incisors were treated by apicoectomy and a retrograde dentin-bonded composite filling. Periapical healing was observed a few months later by radiography. Later, due to root fracture and marginal bone resorption, the apical parts were removed including adjacent periapical bone. A histological and scanning electron microscopic examination of the tissue showed reformation of periodontium adjacent to the composite, including reformation of a lamina dura, inserting Sharpey's fibers and cementum deposited in intimate contact with the composite. This finding is in agreement with previous observations of tissue surrounding retrograde dentin-bonded composite fillings placed in monkeys, indicating that tissue regeneration including cementogenesis may occur on composite material and consequently form a biological closure of the root canal.

Adult↗
PubMed1992

[Results after short- and long-term observations of bone transplantation to vertical, marginal bone defects].

The effect of autologue bone transplantation to 26 vertical, marginal bone defects has been investigated on a long-term scale ranging from 2 to 26 years. The operation technique included excision of gingival pocket epithelium, removal of granulation tissue, and cleansing of the root surface with scalers. The bone cavities were filled preferably with cancellous bone chips, usually from the patients' upper third molar region. After suturing, the area was covered with a wound paste for 12-14 days. Loosened teeth were splinted for at least 2 months. In 25 of 26 teeth (96%) a bone regeneration was observed radiographically. The maximum healing of 22 cases occurred 2-12 months (median 6 months) postoperatively (Table 1). The maximum healing was maintained for more than half of the teeth (56%) at the last control, median 16 years (range 2-26 years), and none of these teeth were extracted of periodontal causes. They might therefore be expected to function for still a long time. Eight teeth (32%) showed more or less recurrence when controlled 5 to 15 years (median 10 years) after operation and 6 of the 8 teeth with recurrence were extracted. Three teeth (12%) developed root resorption and were extracted 6, 10 and 14 years postoperatively. As most of the complications occurred after extended observation periods, this factor has to be taken into account when prognosis of periodontal treatment procedure is considered.

Adult↗
PubMed1991

Retrograde root filling with composite and a dentin-bonding agent. 1.

A method is described, by which retrograde root filling with a composite resin can be performed. The cavity design is a slightly concave dissection of the apical part of the root, which is treated with the bonding agent Gluma followed by an application of Retroplast. Retroplast is a chemically curable composite containing silver for radiopacity and aerosil to obtain a suitable consistency. Endodontically treated teeth with a eugenol-containing root canal sealer did not affect the strength of the bond between Retroplast and apical dentin. A tight seal between the composite and the cavity surface was observed by light and SEM microscopy, and histology of tissue surrounding fillings placed in monkeys revealed absence of inflammatory cells around the filling and a close contact between filling and fibroblasts with collagenous fibers. In some cases, cementum and Sharpey's fibers formed in contact with the filling. Fillings placed in humans performed successfully in most cases, and the main causes of failure were either inadequate hemostasis during filling, or root fracture unnoticed by the time of filling. The retrograde technique promises a new treatment principle, with a root canal effectively sealed and the periapical ligament restored after apicoectomy.

Adolescent↗
PubMed1991

Retrograde root filling with composite and a dentin-bonding agent. 2.

Investigations on retrograde root filling using a composite resin, Retroplast, bonded to the root surface with the dentin-bonding agent Gluma have been described. Here, detailed information is given about the surgical procedures. The aim was to obtain a thin retrograde composite filling on the root apex, made slightly concave, sealing the main root canal, accessory canals as well as dentinal tubules. Hemostasis was obtained primarily by applying 1% adrenaline and by using a needle suction tip, and care was taken not to damage the surrounding tissues by the various chemicals. The healing results, after up to 1 year, of 388 cases of various tooth types, treated with either retrograde composite or with amalgam were compared. The healing classification included four categories: 1) complete healing; 2) fibrous healing; 3) uncertain; and 4) failures. In the composite group, the healing rates were as follows: 74% showed complete healing, 4% fibrous healing, 15% uncertain, and 7% were failures. In the amalgam group, 59% showed complete healing, 3% fibrous healing, 30% uncertain, and 8% were failures. Complete healing occurred significantly more often after filling with Retroplast than after filling with amalgam (p less than 0.00005). Significantly fewer cases with complete healing occurred in lower front teeth in proportion to other tooth types. The number of immediate postoperative complications did not differ significantly between the composite and the amalgam groups.

Bisphenol A-Glycidyl Methacrylate↗
PubMed1989

[Retrograde root obturations employing composite and a dentin bonding agent: adaptions of the filling materials and bond strength].

Composite resin containing silver for radiopacity bonds to the dentin surface of a resected and slightly concave root pretreated with a dentin bonding agent (Gluma). The bond strength between composite and apical dentin is about 18 MPa and is not affected by a preceding root canal filling with eugenol-containing sealer. Contamination with saliva or serum of the Gluma-treated dentin surface reduced the bond strength significantly. No reduction in bond strength is observed when the contamination of the surface is performed before Gluma-application. Microscopy of the borderline between composite and dentin as well as SEM of the composite surface adjacent to dentin revealed a good adaptation which presumably does not allow bacterial penetration.

Composite Resins↗
PubMed1989

[Retrograde root canal filling using resin and a dentin bonding agent: analysis of failures].

With Gluma, an aqueous solution of 5% glutaraldehyde and 35% HE-MA, resin may be chemically bonded to a root surface. In the article failures of apical retrograde root fillings with Gluma and resin (retroplast) were studied, clinically and radiographically, as well as by microscopy of ground sections of extracted teeth or by scanning electron microscopy of loosened retroplast fillings. Out of 52 failures, 23 were not related to retroplast (18 had root fracture). Of the remaining 29 cases, 26 were reoperated. More than half of the failures had loose retroplast fillings. The loosening could be caused by: exceeded working time for the resin or moisture, blood or saliva present on the root before filling, debris on the root surface, possibly because of corrosion, or the presence of phenol in the root canal. In five cases of failure there were denuded root canals. Four cases (of 800) with rapidly developing osteitis might have been due to contamination of bone and soft tissue by EDTA, non-polymerized resin, alcohol or glutaraldehyde.

Aldehydes↗
PubMed1989

[Retrograde root canal filling using resin and a dentin bonding agent: operative procedures].

Using a specially designed filled resin and the bonding agent Gluma, the aims were to obtain a thin retrograde filling covering the slightly concave root surface which would close all root canals and avoid excess filling material. To achieve a strong bond, the resin must be applied to an absolutely dry Gluma surface, free of all traces of blood or saliva. Hemostasis was obtained primarily by applying 1% adrenalin and by use of a needle suction tip. Absence of moisture was obtained by removing all soft tissues from the cavity, using dry compressed air and avoiding condensed moisture from a cool resin. To avoid loosening of the filling, the working time of the resin must not be exceeded, and removal of excess filling material must not be done before polymerization is complete. Contamination of the various chemicals and filled resin must be avoided in order to avoid damage to the surrounding tissues.

Aldehydes↗
PubMed1989

[Retrograde root obturations using resin and a dentin bonding agent: a preliminary histologic study of tissue reactions in monkeys].

The histologic response to a new retrograde root filling procedure using composite and a dentin bonding agent (Gluma) was examined in two monkeys (Cercopithecus aethiops). Infected root canals in canines and incisors were retrograde sealed and a histologic examination performed after 1 year. Among three canines, two showed epithelial proliferation on the resected root surface, apparently originating from the incision which had been placed very close to the level of resection. In the third canine, filled with a composite containing tricalciumphosphate, there was not only reformation of new Sharpey's fibers, but also, seen for the first time, regeneration of new cementum directly upon the retrograde filling material (Fig. 1). Two incisors were extracted, the apices resected, a retrofilling applied, and the incisors replanted. In this way any interference by epithelium could be avoided. After 1 year, both teeth showed a narrow fibrous zone without inflammation opposite the filling material (Fig. 2). The surprising finding that a composite could allow complete PDL regeneration including cementum upon the retrograde material implies that a new biologic retrograde root filling principle is at hand. Experiments are now in progress to further characterize the necessary condition for cementum repair upon composite used as a retrograde root filling material.

Animals↗
PubMed1989

[Retrograde root filling utilizing resin and a dentin bonding agent: indication and applications].

With Gluma a methacrylate-based resin may be chemically bonded to dentin with considerable strength. Resin may therefore be used for retrograde root fillings. Whereas a retrograde amalgam filling demands a box-like preparation, retroplast (Gluma and resin) may be applied to a slightly concave root surface. It may therefore be employed in areas normally inaccessible with amalgam technique. Retroplast can thus be used on roots of all molars and to restore root perforations, root resorptions, cracks, grooves and defects of the root. In addition on lateral canals, on extremely thin roots and to cover perforating root canal posts, this technique can also be used. Dentin/root-cement transplantation may be performed for the purpose of reattachment. The article discusses the technique and its applications with examples showing that it may result in satisfactory healing.

Composite Resins↗
PubMed1989

[Retrograde root filling utilizing resin and a dentin bonding agent: frequency of healing when compared to retrograde amalgam].

Gluma, an aqueous solution containing 5% glutaraldehyde and 35% HEMA, may bond resin chemically to dentin with considerable strength and without cracks. In retrograde root filling, Gluma and resin (retroplast), can adhere to a flat or slightly concave root surface, so that it may be employed to otherwise inaccessible roots. Gluma may cause toxic reactions, but properly used, it is tolerated well. Of 400 consecutive cases with retroplast, 388 were controlled (99 front teeth, 86 premolars and 203 molars) up to 1 year after operation. The healing after these was compared with a series of retrograde amalgams with the same number and distribution in the various tooth types 1 year postoperatively. The result after retroplast was 74% complete healing, 4% fibrous healing, 15% uncertain and 7% failures. After retrograde amalgam 59% complete healing, 3% fibrous healing, 30% uncertain and 8% failures. Complete healing occurred significantly more often after retroplast than after amalgam (P less than 0.00005). After retroplast significantly fewer cases with complete healing occurred in lower front teeth than in other tooth types. There were no significant differences in the occurrence of postoperative complications after retroplast and amalgam. There were two patients with serious osteitis after retroplast.

Composite Resins↗