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Biomedical subjects

J Rozniecki

Publications and source records attributed to J Rozniecki.

At least 109 records · Page 6Linked to original sources

Pulmonary function and histaminemia after polymyxin B inhalation.

Bronchial challenge with polymyxin B caused a significant bronchoconstriction in 85% of atopic asthmatics. In all atopic asthmatics in whom inhalation of polymyxin B elicited bronchoconstriction, a significant, although not always parallel to the grade of bronchoconstriction, increase in histaminemia was observed. If bronchoconstriction was not elicited, the increase in histaminemia did not occur. It constitutes evidence that the bronchoconstricting effect of polymyxin B is exclusively due to degranulation of mast cells and that histamine released in the bronchi can increase the concentration of histamine in the blood.

Adolescent↗

Histaminemia after aspirin challenge in aspirin-sensitive asthmatics.

To determine the role of mast cells in aspirin-induced bronchoconstriction, venous histaminemia was measured in 17 aspirin-sensitive patients before and after administration of aspirin. Ventilatory disturbances were measured spirographically. Venous histaminemia was determined according to Lorenz. In 11 patients the mean increase of histaminemia was from 39.6 ng/ml to 107.0 ng/ml. In the remaining 6 patients no change in histaminemia was observed after the challenge. In patients exhibiting the increase of histaminemia, symptoms of hypersensitivity to aspirin, other than dyspnea, were not common and stronger. The authors discuss a possible relationship of the aspirin effect, disturbances in prostaglandin synthesis and histamine release.

Adult↗

[Relationship between work in nitrogen-processing plants and chronic bronchitis including bronchial hypersensitivity].

The examination involved 55 men exposed to NH3, 60 exposed to NO2 and NH3 and 98 controls. Symptoms of chronic cough and (or) expectoration were found in 8 controls and 18 exposed workers. Significant differences refer only to smokers. Bronchial overreactivity was found in 23.5% controls and in 21.1% of those exposed. The authors conclude that in smokers exposed to NO2 and NH3 chronic bronchitis prevalence is greater whereas occupational exposure did not contribute to an increased number of those suffering from bronchial overreactivity.

Adult↗

Catamenial pneumothorax.

A report is given of a 46-year-old woman, who had nine recurrencies of a catamenial right-sided pneumothorax. During anovulatory hormone treatment no recurrency was noted for the following 6 months.

Chlormadinone Acetate↗