Cloning and nucleotide sequence of two S-RNases from Lycopersicon peruvianum (L.) Mill.
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Alleles↗
Biomedical subjects
J Royo
Publications and source records attributed to J Royo.
The gene for trypsin inhibitor CMe is regulated in trans by the lys 3a locus in the endosperm of barley (Hordeum vulgare L.).
A cDNA encoding trypsin inhibitor CMe from barley endosperm has been cloned and characterized. The longest open reading frame of the cloned cDNA codes for a typical signal peptide of 24 residues followed by a sequence which is identical to the known amino acid sequence of the inhibitor, except for an Ile/Leu substitution at position 59. Southern blot analysis of wheat-barley addition lines has shown that chromosome 3H of barley carries the gene for CMe. This protein is present at less than 2%-3% of the wild-type amount in the mature endosperm of the mutant Risø 1508 with respect to Bomi barley, from which it has been derived, and the corresponding steady state levels of the CMe mRNA are about 1%. One or two copies of the CMe gene (synonym Itc1) per haploid genome have been estimated both in the wild type and in the mutant, and DNA restriction patterns are identical in both stocks, so neither a change in copy number nor a major rearrangement of the structural gene account for the markedly decreased expression. The mutation at the lys 3a locus in Risø 1508 has been previously mapped in chromosome 7 (synonym 5H). A single dose of the wild-type allele at this locus (Lys 3a) restores the expression of gene CMe (allele CMe-1) in chromosome 3H to normal levels.
Amino Acid Sequence↗
Sinonasal undifferentiated carcinoma invading the orbit.
Sinonasal undifferentiated carcinoma (SNUC) is an infrequent tumor described by Frierson et al. in 1986. Since its initial description, fewer than 100 patients have been reported. We present a case of a SNUC invading the orbit in a 57-year-old woman, for which the findings are documented by CT scan, light and electron microscopy.
Carcinoma↗
[Evaluation with acoustic rhinometry of surgical results in patients undergoing septoplasty].
We used acoustic rhinometry to evaluate the surgical results of septoplasty in patients with nasal respiratory insufficiency caused by morphological abnormalities of the nasal septum. Acoustic rhinometry is a relatively new exploration method for the nasal cavity that yields objective spatial measurements. These measurements are the cross sections and volumes of the nasal cavity divided longitudinally into two regions, an anterior region up to 32 mm from the nasal orifices and the posterior region, up to 64 mm from the same point. We studied 45 patients with nasal respiratory insufficiency who had undergone septoplasty. Measurements were made before and after surgery. Our results show a clear increase in nasal sections and volumes after surgery. They confirm the benefits of acoustic rhinometry as a method for quantifying morphological abnormalities of the nasal cavity.
Acoustics↗
[Cavernous hemangioma of the maxillary sinus].
We describe a case of maxillary sinus hemangioma which originated in sinusal mucosa and which extended into the nasal cavity. Clinical and radiologic findings are presented and the literature reviewed. Surgery appears curative in most cases.
Adult↗
[Cold retropharyngeal abscess associated with cervical vertebral tuberculosis].
A 38-year-old man, parenteral drug user affected by vertebral tuberculosis with involvement of the first, second and third cervical vertebrae associated with a cold retropharyngeal abscess is presented. Treatment and main clinical and histopathologic features of this very unusual location of tuberculosis are discussed.
Adult↗