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Biomedical subjects

J Royer

Publications and source records attributed to J Royer.

At least 55 records · Page 3Linked to original sources

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France↗

[Congenital microcoria: a case report with histopathological study].

The authors report a case in which congenital microcoria was associated with glaucoma; a complete histopathological study was performed and the relation between microcoria and glaucoma was considered. The association with extra-ocular abnormalities, particularly renal lesions is noticed.

Anterior Chamber↗

[The dry eye].

Dry eye, or keratoconjunctivitis sicca, is a pathologic condition which, today, needs to be more precisely defined. The moisture in the eye, which is essential for optical and physiological reasons, is maintained by three factors: a) the secretion of mucus by the conjunctiva, rendering uniform distribution of the aqueous phase of the lacrimal film on the corneal surface possible; b) the secretion of aqueous humor by the lacrimal and conjunctival glands; and c) the secretion of lipids from the skin and meibomian glands. Accordingly, an insufficiency of the lacrimal film may be due to insufficient secretion of lipids from the skin or meibomian glands, insufficiency of the aqueous phase of the lacrimal film (as is the case in Gougerot-Sjögren syndrome), or insufficiency of the mucus secretions (as in the case of pemphigoid syndrome). The complaints which lead patients to consult an ophthalmologist, as well as the objective findings on examination, are described here. The methods of examination by which lacrimal insufficiency can be confirmed are discussed: Schirmer's test (I and II), Jones' test, Norn's dilution test, break-up time, tests with dyes such as fluorescein, rose bengal, and lissamine green 1%. The conjunctival imprint gives indications without which no clear diagnosis can be made. The treatment of dry eye consists primarily of instillations of artificial tears. If this treatment fails the lacrimal puncta can be closed. Thirdly, pathogenic treatments can be used in certain cases. Fourthly, one can prescribe closed frames which create a wetting chamber. Finally, in particularly severe cases, surgery can be considered.(ABSTRACT TRUNCATED AT 250 WORDS)

Combined Modality Therapy↗

[Conjunctival impression in the keratoconjunctivitis sicca syndrome].

Cytological study is extremely useful in supplementing clinical findings in various conjunctival and corneal conditions. The authors describe a simple, reproducible, and painless method - impression cytology - for removing conjunctival tissue. It is cheap and quick, and can also be used for outpatients. The sample is spread flat on a light microscope slide and cytologically evaluated, e.g., with regard to perilimbal distribution of the mucus cells, cell nucleus-cytoplasm ratio and serpiginous aspect of the chromatin. The method permits more objective evaluation than is possible with conventional biopsy methods. It is particularly suitable in dry-eye syndrome and hypersecretion of the mucus cells. By repeating the procedure information can be obtained about the course of the disease and the efficacy of therapy.

Conjunctiva↗

[Computer management of the data of automated perimetry using Octopus 2000 R].

Current perimetry involves automated, static and punctual procedures, which permit the examiner to obtain a numerical value of the sensibility concerning the points tested. Besides its precision and its reliability, perimetry can be used in data processing management due to the characteristic of easy duplication of the examinations. We use a micro-computer which is seperate from the Octopus 2000 R (Apple IIc) and the disc (OmnisII) to process the files. The study is composed of the following areas: the storage and the data processing of patient files, the transformation of numerical data a graphics display, the study of the percentage of loss of surface according to the decibel of sensibility. The data processing of files improves storage according to the criteria defined by the examiner and helps avoid inconvienent research. The graphic transformation of numerical data into isopteres of chosen sensibility improves the definition of the zones of intermediate sensibility. The calculations of the percentage of loss of surface according to the decibel of sensibility allows the appreciation of the size of defects based on depth and quantification. It is also easy to make the comparison between the two fields.

Aphakia, Postcataract↗

[Statistical analysis of visual fields by the automatic perimeter Octopus 2000 R with the Delta program].

The difference tables gives, on a numeric table, the difference between first and second examination. The confidence interval is given out by a statistical test (T-test) which can be applied to the following parts of visual field: pathological area, whole field. We present a number of visual field examinations (Program 33) from glaucomatous patients, analysed through "change mode". We can make the following remarks: When we assess an improvement, it is underlined in "Delta Program", which indicates: significant improvement. When the visual field is unchanged, "Delta Program" indicates a fluctuation: aggravation or improvement (almost always insignificant). A subjective alteration is always underlined by "Delta Program". The program allows an objective interpretation and, when it is combined with the usual objective interpretation, makes the evaluation of campimetric deficiency easier. The importance of statistical analysis, besides the fact that it associates the visual field to one or several mean values, is to set it off as exactly as possible. Flammer and coll. (1985) propose a new index: "corrected loss variation".

Computers↗

[Automated and semiautomated perimetry. Comparative trial of 3 devices (Baylor programmer, Friedmann Mark II campimeter, Octopus 2000 R.)].

Modern perimetry involves automated or semi-automated procedures, this computer assisted perimetry (CAP) providing results independent of the examiner, and with marked discrimination of light sensibility through quantification of points tested. A wide variety of CAP devices are available, and a comparative study was conducted in 50 patients using 3 perimetric apparatuses with similar supraliminal static techniques but with variable automated potentials: The Goldman perimeter modified by "Baylor visual fields programmer": static technique for the middle area and kinetic for the peripheral area. The Friedmann Mark II Visual Fields Analyser with a multiple stimulus static technique for the middle area. The Fankhauser Octopus 2000 R perimeter with a precise static technique for middle and peripheral areas. This perimeter, highly automated, also allows statistical evaluation of defects changes, owing to storage of results on magnetic discs. Patients studied had either: glaucoma (25 cases) or neuro-ophthalmologic and retinal disorders (24 cases). Conclusions drawn from the experience acquired by the authors during more than one year of use of the 3 devices were: Rate of detection of defects is excellent with the Octopus and quite good with the Friedmann MKII, but limited in the middle area. The Baylor program does not allow quantification of defects. The image is clear with the Octopus as far as the gray scale is concerned, and more exact as far as the comparative tables are concerned; is not clear with the Friedmann MKII; is typical and clear with the Baylor. The length of examination (which varies with the programs used as far as the Octopus is concerned, and with the patient's reaction time) is usually long with the Octopus and the Friedmann, but short with the Baylor. Time and energy can be gained by the use of the Octopus, since it supplies data obtained from use of the Baylor program associated with that of the Friedmann MKII. The authors prefer to follow up campimetric evolution of glaucomatous patients with the Octopus because it offers more sensibility and precision in quantifying losses. The application of the statistical evaluation delta program on the 2000 R device, which will soon be tested in the Ophthalmological Department, could in an objective way indicate whether there is stabilization or a real progression of glaucomatous defects.

Adenoma↗