[Histogenesis of bronchial secretory IGA].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to J Roujeau.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The desquamative intersitial pneumonia is a rare, sometimes curable from of diffuse interstitial fibrosis. A clinical, optical and ultrastructural, immunochemical and histo-enzymologic study of one case proved the macrophage nature of the intra-alveolar cells and suggested in the histo-genesis an immunological mechanism depending on lymphocytes.
The mortality statistics due to tuberculosis drawn up by INSERM for the years 1968-1973 show the rate to be 0.86% in the Paris region. A study based on autopsy results of 7,400 adults gave a rate of 3.3%. The causes of this discrepancy are analysed.
The authors report 3 cases of refractory fulminant hypoxemia. The etiology was various, neoplastic lymphangitis, influenza and tuberculosis. The authors emphasize the role of tuberculosis in the onset of certain diffuse interstitial fibroses.
The authors report a case of diaphyseal bony tuberculosis, in which the diagnosis was not made for a long time as bony tuberculosis is considered exceptional and owing to the presence of a staphylococcus which oriented the diagnosis towards osteomyelitis. Bony tuberculosis certainly affects more easily immigrant patients, in whom one may see multifocal forms, but also affects those who, by their environment, might imagine they are protected, and it is not exceptional to see unifocal forms.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
All the examples quoted demonstrate that in the field of toxicology, pathologic anatomy still offers the means of establishing the first links between macroscopic and microscopic lestions and physiology. The current trend in this disciplin is to look beyond the clinical symptom or morphologic disturbance and seek the causal biochemical interactions. Through the methods of systematic autopsy and electron microscopy of biopsy specimens, pathologic anatomy continues to provide the alarm signal for the pharmacologic warning system our modern environment demands.
Explore the source record for details and available documents.
Concentrated irradiation (two series of 1,800 rads in 2 sessions and 3 days) separated by a rest period of 3 to 4 weeks has been used to treat 214 adult patients with brain tumors between 1965 and 1972. These included 108 glioblastomas, 18 astrocytomas and 88 brain metastases from different origins. Early side effects are moderate or inexistent provided synthetic ACTH or corticoid steroids have been given several days before irradiation. Survival is related, at least, in the first 2 groups of primary tumor to local failure. For brain metastases, death could be related to others reasons. In spite of the fact that comparison is made with a previous series of 121 cases it seems that this type of irradiation gives the same survival rates. Moreover it has specific advantages as reducing duration of hospitalization and the number of treatment sessions.
Explore the source record for details and available documents.
Explore the source record for details and available documents.