Search PubMed⌕ Search

Biomedical subjects

J Rose

Publications and source records attributed to J Rose.

At least 217 records · Page 12Linked to original sources

Regional categorization and quality of care in major trauma.

A statewide evaluation of major inpatient trauma treatment was completed demonstrating the relationship of emergency medical service categorization and quality of trauma care. Demographic and organ injury data provided guidelines for preventive and medical education emphasizing the need for more practical sessions. The differences between the review process of primary care physicians and specialists was also discussed.

Adolescent↗

Evaluation of the quality of hospital care for major trauma.

A retrospective analysis of trauma care in five hospitals was undertaken. Eight hundred twenty-three charts met criteria for major trauma. A panel of surgeons reviewing 237 selected charts found the quality of care unacceptable in 16%. Unacceptability rates between hospitals ranged from 7 to 58%. Injury severity score rather than length of stay appears to be a better method for selecting patients at greater risk for poor care.

Accidents, Traffic↗

Isolation and partial characterization of single-stranded adenoviral DNA produced during synthesis of adenovirus type 2 DNA.

Single-stranded fragments of adenovirus type 2 DNA were isolated from infected KB cells under conditions which retarded reassociation of complementary sequences but did not denature native viral DNA. Of the total intracellular, virus-specific DNA labeled during a 1-h pulse with tritiated thymidine begining 15 h after infection, about 20% was single stranded when fractionated on hydroxylapatite. This DNA shifted predominantly to the double-stranded fraction on hydroxylapatite during an extended chase incubation, suggesting that it may represent single-stranded DNA in replicating intermediates. Furthermore, the single-stranded DNA annealed nearly equally to both strands of the adenovirus genome. These findings indicate that at least portions of both complementary strands of adenovirus type 2 DNA are exposed as single strands during the period of viral DNA synthesis.

Adenoviridae↗