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Biomedical subjects

J Roquer

Publications and source records attributed to J Roquer.

At least 73 records · Page 4Linked to original sources
PubMed1984

Leigh's syndrome in an adult.

A 55-year-old man with a subacute onset of slurred speech, ataxia, nystagmus, extrapyramidal rigidity, decreased tendon reflexes, vomiting, bilateral optic atrophy, and clonic jerks died of bronchopneumonia and respiratory failure. Neuropathological examination showed lesions characteristic of subacute necrotizing encephalopathy. Clinicopathological observations of reported cases of Leigh's syndrome in the adult are reviewed.

Brain↗
PubMedDate not supplied

Intracerebral haemorrhage in AIDS.

We report 8 patients with the acquired immunodeficiency syndrome (AIDS) and intracerebral haemorrhage. There were 7 men and 1 woman (mean age 37.2 years) with a mean CD4 count of 81.2/mm3. Alcohol abuse was recorded in 7 patients, intravenous drug use in 4, homosexual activity in 2, thrombocytopaenia in 1 and severe hypertension in 1. There were 5 lobar and 3 deep haemorrhages. Potential aetiologies of intracerebral haemorrhage included cerebral toxoplasmosis (n = 2), thrombocytopenia (n = 2), hypertension (n = 1) and cerebral tuberculosis (n = 1). Data of these patients were compared with those of 30 AIDS inpatients without brain haemorrhage matched by age and sex and no statistically significant differences in risk factors for AIDS except for alcohol abuse (> 80 g/day) (p = 0.045) were found. Causes of brain haemorrhage in AIDS patients are heterogeneous. The relationship between both conditions may be explained by the effect of several predisposing factors to stroke in association with AIDS-related complications. Intracerebral haemorrhage is a late and serious complication of AIDS (mortality 62.5%). The frequency of intracerebral haemorrhage in AIDS (1.0%) is higher than that expected in a general population of young adults.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

Hyperthyroid myopathy with mitochondrial paracrystalline rectangular inclusions.

The ultrastructural features of a case of severe hyperthyroid myopathy are presented. Along with the moderate increase in mitochondrial size and number usually observed in most patients with hyperthyroid myopathy, some of the skeletal muscle mitochondria in the present case also contained paracrystalline rectangular inclusions. This finding has not been previously reported in hyperthyroid myopathy and further supports the current view that mitochondrial abnormalities play a major role in the pathogenesis of muscle dysfunction in hyperthyroid patients.

Aged↗
PubMedDate not supplied

Meningeal melanocytoma: a case report and literature review.

The clinicopathologic, immunocytochemical, and electron microscopic features of a case of meningeal melanocytoma arising in the phylum terminale are reported. Meningeal melanocytoma is an uncommon tumor that must be distinguished from metastatic or primary malignant melanoma, meningeal melanocytic nevi, pigmented meningioma, pigmented schwannoma or neurofibroma, and pigmented primitive neuroectodermal tumor. This is a difficult differential diagnosis that can be best archived by complementing histological examination with a selected panel of antibodies and, most important, electron microscopic study. The distinctive ultrastructural appearance of most of these lesions point to this technique as the gold standard in pigmented proliferations of the nervous system.

Aged↗
PubMedDate not supplied

[Moyamoya syndrome. Diagnosis with angio-MRI].

We present a case of Moya-Moya syndrome in a 28-year-old female patient with an unusual debut in the form of mirror-image writing. The patient was studied by CAT, conventional cerebral angiography, MRI and angio-MRI. The results obtained show a very good correlation between the images of conventional angiography and those obtained by angio-MRI. Angio-MRI requires no contrast, is noninvasive and rapid, promising to be a first class alternative in the diagnosis and follow-up of Moya-Moya syndrome.

Adult↗
PubMedDate not supplied

[Hemangioblastoma associated with syringomyelia and syringobulbia in a patient with rheumatoid arthritis].

A 80-year-old woman with a 25-year history of seropositive, erosive rheumatoid arthritis (RA) presented with a neurological clinical picture consistent with cervical cord compression, secondary to a hemangioblastoma with medulla, cerebellum and spinal cord involvement, with associated syringomyelia and syringobulbia. We present a review of the literature remarking the low frequency of this tumor (1%-2% of all intracranial tumors) and its exceptional presentation over the age of 70. We have not been able to find no cases of hemangioblastoma associated with rheumatoid arthritis, thus, we think, this association may be casual. Nevertheless, it emphasizes the need for careful evaluation of patients with rheumatoid arthritis and neurological symptoms before ascribing them to complications due to the rheumatoid disease itself.

Aged↗
PubMedDate not supplied

[Anterior choroid artery syndrome. Study of 3 cases].

Three cases of anterior choroid artery are reported, representing 0.80% of all strokes admitted to our Service in the last 3 years. Their clinical features were manifold and only motor involvement was common to the 3 patients, although with varying intensity and topography. In one case there was pure motor hemiparesis. Only one patient had sensory impairment, whereas none had defects in the fields of vision. In the 3 patients, CT showed the characteristic hypodense image limited to the posterior limb of the internal capsule, whereas EEG was normal in the 3 patients. The clinical outcome was very satisfactory in one patient and fair in the other two, with persisting sequelae which did not prevent an autonomous lifestyle.

Aged↗
PubMedDate not supplied

[Pronator teres syndrome. Clinical and neurophysiological study of 2 cases].

We report two cases of pronator teres syndrome (bilateral in one case) diagnosed in our Department by electromyographic studies during the last three years. The infrequency of this syndrome (1 case/201 cases of carpal tunnel syndrome), combined with the unspecified and inconsistent symptomatology (tenderness over the pronator teres, paresthesias and weakness of flexor pollicis longus, abductor pollicis brevis and opponens pollicis) frequently induced diagnostic mistakes. The electromyographic study is very useful showing a delay in proximal motor latency of the median nerve, diminution of motor nerve conduction in the proximal forearm segment of this nerve with normality of distal motor latency and sensory latency. Corticoid infiltration is the treatment of choice keeping in reserve surgery only for resistant cases.

Adult↗