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Biomedical subjects

J Rondier

Publications and source records attributed to J Rondier.

66 records · Page 4Linked to original sources
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[Hyperlipemias and their manifestations in the rheumatological sphere].

It is fairly frequent to encounter hyperlipemia on a rheumatic unit. Firstly the symptoms of certain idiopathic hyperlipemias sometimes include rheumatic changes. The latter include firstly, arthritis and tendinitis, above all observed in Type II hyperlipoproteinemia but also mentionned in Type IV, and secondly, exceptional bony lesions (generally of xanthoma type) which seem to occur exclusively in severe hyperglyceridemia. A few bone and joint diseases, such as gout or aseptic necrosis, frequently coexist with dyslipemia. Furthermore, various diseases may be simultaneously responsible for secondary hyperlipemia and involvement of the locomotor apparatus. Finally, the iatrogenic manifestations of the locomotor system appear mainly due to hypolipemic drugs, e.g. the muscle disorders seen in a few patients treated with clofibrate.

Adrenocortical Hyperfunction↗
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[Muscular metastasis, first symptom of bronchial carcinoma (author's transl)].

One case of bronchial carcinoma in which a muscular metastasis was the presenting symptom is reported. Clinical features included pain and gradual swelling of left musculus supra-spinatus. Surgical biopsy showed intra-muscular metastasis of bronchial origin. Radiotherapy provided transient pain relief, but the patient died 15 months after the first symptoms. Metastatic tumors of skeletal muscles are found in some cases, when carefully searched for in routine autopsy surveys. Most of these tumors remain asymptomatic; in other cases clinical picture includes pain, swelling and diffuse or nodular induration of the involved muscles. Biopsy shows metastatic tumor in these muscles, which generally retains the same growth pattern as seen in the primary tumor.

Aged↗
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[Sciatica in the elderly. Apropos of 27 cases operated after the age of 70].

From a study of 27 operations for common vertebral sciatica in the elderly, certain specific features stand out. L5 sciatica is predominant though curiously, the pain relieving posture is less frequent than in the S1 variety. The condition is usually most painful at night. In 50% of cases there is a motor deficit which to a great extend determines the decision to operate. Finally, there is very good correlation between clinical features and the discovery of a prolapsed disc. Osteoarthrotic lesions are much more common than in the general sciatica population but the disc protrusion always keeps its localising value. Surgical intervention reveals that the disc plays an equally important role at this age as a prolapsed disc was found in 26 cases (11 extruded herniated discs and 2 ruptured). These lesions are less common in the general sciatica population. In about two thirds of patients a herniated disc alone is found and in the others, it is associated with osteoarthrotic lesions although these do not appear to compromise the success of the operation. Amongst the 9 post-operative complications, there was one death due to pulmonary emboli and 2 cases of reflex algodystrophy of the foot on the operated side. With a mean delay of more than 1 year, a frank improvement was noted in 85% of cases as against 80% immediately following surgery. Only one case of recurrence was reported.

Age Factors↗