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Biomedical subjects

J Rochemaure

Publications and source records attributed to J Rochemaure.

At least 145 records · Page 8Linked to original sources
PubMedDate not supplied

[Angiofollicular lymphoid hyperplasia (Castelman's tumor) in the mediastinum. Apropos of 2 cases].

The authors report two new cases of angiofollicular hyperplasia of the mediastinum (Castelman's tumour). The only clinical peculiarity was a rapid increase in volume. The authors then review about 200 published cases. Emphasising the existence of 3 different histological types (plasma cell form, vascular hyaline form and intermediate form) and on the association in certain cases of hematological disorders such as anemia and hypergamma globulinemia. The significance of this lesion is discussed. An inflammatory theory with reactional hyperplasia of the beta-lymphocytes is proposed. It was supported by a direct immunofluorescent study of two cases (first study of this type carried out on such lesions) which showed polyclonal plasma cell hyperplasia predominating on the IgG.

Adolescent↗
PubMedDate not supplied

[Bronchopulmonary adenocarcinomas of apparently primary origin. A retrospective study of sixty-six patients (author's transl)].

A retrospective study of sixty-six case-reports confirmed the traditional factors described in this histological type of cancer, particularly the age, a slight predominence of males, and the very poor prognosis. A selection was made of 42 cases in which extensive investigations had been carried out to search for a possible extrapulmonary primary adenocarcinoma, but only one case of renal cancer and one of thyroid cancer were demonstrated. Autopsy had revealed the presence of 3 prostatic lesions and their relation to the pulmonary affection is discussed. Thyroid cancer had been found in 2 cases, which emphasizes the value of scintigraphy for this organ, whereas the authors felt that other investigations were of no value in the absence of clinically oriented signs.

Adenocarcinoma↗
PubMedDate not supplied

[Sarcoidosis associated with tuberculosis. A study of seven patients (author's transl)].

The authors studied seven patients with sarcoidosis and tuberculosis: the affections co-existed in 3 cases but were separated by varying intervals of time in the 4 other patients. They discuss the diagnostic, therapeutic, and nosological problems posed by these cases, and review the various hypotheses that have been suggested to explain these associations in relation to the pathogenesis of the sarcoidosis.

Adult↗
PubMedDate not supplied

[Value of quantitative evaluation of bacterial species in bronchitic infections (author's transl)].

A quantitative evaluation of the bacterial species in the sputum collected from 93 patients was conducted over a period of 7 months. The patients were divided into five different pathological categories, while separating those patients who had not received antibiotic therapy before samples were taken from those who had been administered this type of treatment. Samples were repeated after one week in 30 cases. The most frequently encountered germs were hemophilus (10(6)) and pneumococcus (10(7)). In simple bronchopathies, Gram-negative germs were only isolated at levels of 10(5) from patients previously treated with antibiotics, which demonstrates their low pathogenic role. In most severe bronchopathies they were isolated more frequently, but at levels which rarely exceeded 10(6). Their pathogenic role has to be evaluated as a function of the progression in clinical signs. The authors underline the frequency with which pneumococcal strains are resistant to tetracyclines.

Anti-Bacterial Agents↗
PubMedDate not supplied

[Association between bronchial dilatation and male sterility].

The frequency of associated bronchial dilatation and male sterility is sufficiently high for simple coincidence to be discounted. Initially observed in patients with Kartagener's syndrome, an abnormal frequency of bronchial disorders (with or without ectasia)M was then noted in subjects with azoospermia, especially of the excretory type. Originally proposed by AFZELIUS et al in 1975, an explanation for the association could be the presence of ultrastructural anomalies of the cilia, both in the bronchial mucosa and in the single cilium of the spermatozoid. Other physiopathological explanations for this association, characterized by a motility disorder (mucociliary or spermatic), include secretory anomalies as in mucoviscidosis and acquired anomalies (major role of infection in bronchial affections, role of tobacco). Practical consequences of this association are discussed.

Bronchi↗
PubMedDate not supplied

[Infective pneumopathies of immunosuppression].

Advances in the therapy of tumors or for the maintenance of grafts have improved survival in a large number of patients, but at the price of repeated complications due to the induced immunodeficiency state. Pulmonary infections are a frequent occurrence, and while some are easily recognized and treated, others must be precisely diagnosed, as only early specific treatment can avoid the often fatal outcome. Various techniques have therefore been developed to obtain specimens for microorganism isolation before having ultimate recourse to a surgical lung biopsy. It is in this field that the most marked progress is currently being made. The different microorganisms responsible for these affections are reviewed, the majority being common to the immunodeficiency state, while others are encountered more frequently as a function of the underlying disorder and of the ecological conditions in each centre.

Aspergillosis↗
PubMedDate not supplied

[Mechanisms of diurnal hypercapnia in sleep apnea syndromes associated with morbid obesity].

OBJECTIVES: The prevalence and mechanisms of diurnal hypercapnia in subjects with sleep apnea syndrome are not well known, particularly in the morbidly obese. METHODS: We studied a group of 24 subjects with sleep apnea syndrome and morbid obesity defined as a body mass index greater than 40 kg/m2 and free of chronic respiratory disease. RESULTS: Hypercapnia (PaCO2 > 42 mmHg) was found in 50% of the subjects. Age, body mass index, waist/hip ratio, apnea index, ratio of maximum forced expiratory volume in one second (FEV1) to vital capacity and expiratory reserve volume were not significantly different between hypercapnic and normocapnic subjects. Total pulmonary capacity, vital capacity and FEV1 were significantly lower in hypercapnic subjects than in normocapnic subjects. CONCLUSION: These findings suggest that ventilatory restriction plays an important role in the development of diurnal alveolar hypoventilation in subjects with sleep apnea syndrome and morbid obesity.

Adult↗