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Biomedical subjects

J Roberts

Publications and source records attributed to J Roberts.

At least 739 records · Page 41Linked to original sources
PubMedDate not supplied

Hepatic focal nodular hyperplasia: CT and sonographic spectrum.

Fifteen patients with pathologically proven focal nodular hyperplasia (FNH) of the liver had abdominal computed tomography (CT) (15) and ultrasound (11). In seven patients, the lesions were incidentally found during gallbladder or renal examination, whereas the other eight had a primary neoplasm and the liver was studied for possible metastasis. In 11 unenhanced CT scans, the ratio of isodense to hypodense lesions was 8 to 3. In 15 contrast-enhanced CT scans, seven were isodense, six were hypodense, and in two, the lesion enhanced (hyperdense). In seven patients a hypodense lesion on unenhanced CT became isodense with contrast injection. Delayed images in three showed the lesions appearing as hypodense in two and displaying a rim of enhancement in one. In one case, unenhanced CT was normal and only enhanced CT showed an area of homogeneous increased density. Ultrasound was done in 11 patients, the lesion was hypoechoic to the liver in five, echogenic in four, and isoechoic in two. Findings of central scar were seen on CT and ultrasound in three cases. Pathologic diagnosis was available in all cases, seven by needle aspiration and eight by surgical resection. In our experience, FNH has many CT and sonographic features that can mimic hemangioma or metastasis. While the presence of a central scar increases the specificity, in a cancer patient, the findings should be interpreted with caution and needle aspiration should be obtained.

Adult↗
PubMedDate not supplied

Epidemiological investigation of Taenia solium taeniasis and cysticercosis in a rural village of Michoacan state, Mexico.

We performed a survey for taeniasis and cysticercosis among persons living in a Mexican village where Taenia solium infection in pigs was known to be enzootic. A standardized questionnaire was administered in all 577 households to obtain medical histories and information on demographic and environmental factors and on risk factors associated with transmission of infection. Serum and/or stool specimens were obtained from 1005 volunteers and examined for cysticercosis antibodies and intestinal parasites. Faecal examination of 828 participants revealed infection by Taenia sp. in 2 (0.2%). Three additional cases of taeniasis were detected in individuals who evacuated proglottids after treatment with praziquantel. Of 1005 human serum specimens, 49 (4.9%) were positive in the cysticercosis immunoblot assay. Seropositivity increased with age and reached a peak in subjects aged 46-55 years (P < 0.05). A history of seizures was significantly associated with seropositivity (P < 0.05); approximately 25% of persons with such histories were seropositive. Histories of headache, dizziness, trembling, blurred vision, and vomiting were also significantly associated with positive immunoblot assays. This study has demonstrated previously undiagnosed morbidity associated with T. solium neurocysticercosis and identified community behavioural and environmental practices that must be modified to prevent continued transmission of cysticercosis and taeniasis.

Adolescent↗
PubMedDate not supplied

Obstetrics by ear. Maternal and caregiver perceptions of the meaning of maternal sounds during second stage labor.

In a study at the University of Colorado School of Nursing, Department of Nurse-Midwifery, women's second stage labors were videotaped to study caregiver behavior during second stage labor. Postpartum interviews of the mothers (n = 10) and caregivers (n = 16) were conducted to learn about their responses as they viewed the videotapes. Qualitative analysis was conducted of the transcribed interviews using the Ethnograph computer software. One of the themes emerging from the data was the significance of maternal sounds. Both caregivers and mothers were able to articulate differences between adaptive and nonadaptive sounds according to their quality, pitch, feeling state, and accompanying verbalizations. Data about women's second stage labor sounds have been categorized according to the following maternal states: work/effort, coping, childlike, out-of-control, and with epidural anesthesia. Typical sounds/verbalization, significance, and facilitative caregiver responses are defined for each category. It is concluded that when a "no noise" rule is evoked during second stage labor, valuable behavioral cues are unavailable to guide caregiver behavior.

Adaptation, Psychological↗