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Biomedical subjects

J Rivière

Publications and source records attributed to J Rivière.

At least 19 recordsLinked to original sources

[Self-produced locomotion and spatial cognition: a new light from spinal muscular atrophy].

Various studies have shown that occurrence of locomotion in infancy is correlated with the development of visuospatial cognitive competencies, suggesting that locomotor experience might play a central role in spatial development, especially in the realm of manual search for hidden objects. However, recent studies indicate that young children with spinal muscular atrophy (SMA), a hereditary neuromuscular disease which results in severe motor impairments, excel in some spatial cognitive skills. Indeed, striking cognitive performances are exhibited by young SMA children in some areas such as the ability to search successfully for hidden objects and the acquisition of the spatial vocabulary. The performances of SMA children suggest that, despite their total deprivation of locomotor experience, they have the capacity to acquire and use rich spatial representations. As a result, locomotor impairment does not appear to be a key risk factor for dramatic slowing down or deviation in the development of spatial search skills.

Child↗

[Spontaneous regression of a sub-adventitial cyst of the popliteal artery].

We report a case of spontaneous regression of a cystic adventicial disease of a popliteal artery in a 37 years old man. The peroperative resection of the adventicia give us the histologic confirmation of the diagnostic. The cyst's content may have gone through either in the peri-arterial space or through a communication with the articulation of the knee. For us, it seems to confirm the embryologic theory for the pathogenic of this disease.

Adult↗

[A new case of arterial Listeria infection].

Listeria monocytogenes arterial infections are uncommon and usually occur on aneurysms of previously operated arteries, classically in very young and very old or immunodepressed subjects. Peroperative samples for bacteriology should always be taken as antibiotics generally used in vascular surgery are ineffective against listeria. We report a case of a patient who underwent emergency surgery. Bacteriologic analysis of the thrombus revealed listeria inoculation which was eradicated by adapted antibiotic treatment.

Aged↗

[Long occlusion of the superficial femoral artery: revascularization by venous graft].

In long occlusions of the superficial femoral artery, possibilities of revascularization depend on the patency of the above-knee popliteal artery. In case of occlusion of the above-knee popliteal artery, the distal anastomosis is to be performed at the below-knee level or more distally; in this situation, studies demonstrate a clearcut superiority of venous bypasses over prosthetic bypasses. Patency of the above-knee popliteal artery allows to perform a shorter bypass avoiding to cross the knee joint; given comparable results between venous and prosthetic above-knee bypasses in certain series, several authors advocated the preferential, if not systematic use of prosthetic materials at this level; this attitude having the advantage of preserving the saphenous vein for later coronary or distal grafting. A critical analysis of studies advocating this therapeutic option reveals that results of prosthetic and venous above-knee bypasses are equivalent in only very restrictive clinical situations (claudication, good runoff) and for follow up less than 3 years; beyond this follow up, the use of a prosthesis increases the number of secondary procedures necessary for maintaining or restoring patency and for this reason increases slightly the overall mortality owing to the operative mortality associated with each reoperation. Apart from rare cases represented by fragile and high-risk patients, whose lifespan is likely to be short and in whom a quicker operation is advisable, indications of the use of prosthetic grafts depend on the limits of the use of the saphenous vein generated by a poor quality or an insufficient diameter.

Anastomosis, Surgical↗

[Thoracic splanchnectomy under video-thoracoscopy].

The technique of thoracic splanchnicectomy under video thoracoscopic control is described. This little aggressive surgical operation is indicated for very painful forms of pancreatic cancer and for some cases of chronic pancreatitis. It should relieve pain for a longer period than splanchnic nerve injection or radiotherapy.

Humans↗

[Anorexia nervosa and pregnancy].

We report the case of a pregnancy associated with severe anorexia nervosa. The patient weighed 33 kg for 1 m 51 at conception. The pregnancy was obtained during a spontaneous cycle. Despite nutritional and psychological case, the patient continued to lose weight and weighed only 28 kgs at 33 weeks of amenorrhea, when she gave birth to a hypotrophic child of 1130 gr after artificial starting. The case provides discussion of the relation ship between anorexia nervosa and pregnancy.

Adult↗

[Non-hormonal therapy for menopausal disorders: results of a multicentric double-blind trial (author's transl)].

A multicentric trial was conducted under double-blind conditions to assess the efficacy of veralipride in the treatment of menopausal disorders, when compared with placebo. Excellent or good results were obtained in 32 of the 40 patients (80 p. cent) with sudden flushes, after veralipride treatment, and only 17 of the 35 patients (48,5 p. cent) after placebo. In spite of the remarkable sensitivity of these disorders to placebo administration, the results are highly significant (p < 0-01) in favor of veralipride. Successful results after veralipride were more frequently noted in cases of natural menopause (21 out of 23 cases = 91,3 p. cent) than those with an artificial menopause (11 out of 17 cases = 64,7 p. cent). In psycho-functional disorders (anxiety, irritability, depressive syndrome), veralipride gave excellent or good results in 17 out of 32 cases, placebo in 8 out of 31 cases, a significant difference in favor of veralipride (p < 0,05). No significant modifications in biological parameters studied were noted, and only 2 cases of mild galactorrhea and mammary congestion were observed, though not reported by the patients. One patient complained of vertigo. Veralipride appears, therefore, to be the first non-hormonal therapy effective against disorders of the climateric.

Adult↗