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Biomedical subjects

J Ricke

Publications and source records attributed to J Ricke.

53 records · Page 3Linked to original sources

Wavelet versus JPEG (Joint Photographic Expert Group) and fractal compression. Impact on the detection of low-contrast details in computed radiographs.

RATIONALE AND OBJECTIVES: The aim of this study was to evaluate different lossy image compression algorithms in direct comparison. METHODS: Computed radiographs were reviewed after compression with Wavelet, Fractal, and Joint Photographic Expert Group (JPEG) algorithms. For receiver operating characteristic (ROC) analysis, 54 thoracic computed radiographs (31 showing pulmonary nodules) were compressed with a ratio of 1:60. Five images of a test-phantom were coded at 1:13. All images were reviewed on a PC. Uncompressed images were reviewed at a PC and at a radiologic workstation (with image processing). RESULTS: For thorax images, decrease of diagnostic accuracy was significant with Wavelets. Fractal performed worse than Wavelets. No ROC curve was observed for JPEG due to poor image quality. No diagnostic loss was noted comparing PC and Workstation review. For low-contrast details of the phantom, results of Wavelet compression were equal to uncompressed images. Fewer true positives and increased true negatives were noted with Wavelets though. Wavelets were superior to JPEG, and JPEG images were superior to Fractal. Workstation review was superior to PC review. CONCLUSIONS: Only Wavelets provided accurate review of low-contrast details at a compression of 1:13. Frequency filtering of Wavelets affects contrast even at a low compression ratio. JPEG performed better than Fractal at low and worse at high compression ratio.

Algorithms↗

[How certain is teleradiological telediagnosis for the tomographic procedure?].

PURPOSE: To define the value of teleradiographic studies, a comparison was carried out between digitised copies of CT examinations of the skull with the original images. Differences in image quality obtained from a digital scanner and a camera were quantified. MATERIAL AND METHOD: 56 CT examinations of the skull, 28 of which had discrete abnormalities, were chosen for ROC analysis. The original films were digitised with a Vidar VXR-12 scanner and Panasonic WV-160 and WV-BP 500 cameras. The images were evaluated by five radiologists after image transfer with Video Conference software to a personal computer. RESULTS: For the analysis of the films the area under the ROC curve was 0.91 +/- 0.04, for the digital scanner it was 0.85 +/- 0.04, for camera WV-BP 500 0.89 +/- 0.06 and for camera WE-160 0.87 +/- 0.09. Comparison with the film findings showed. a minimal p-value of 0.17 which indicated that there was no significant reduction in diagnostic value following digitization. CONCLUSION: The probable reason for the slight deterioration using the digital scanner was the reduction to 75 dpi compared with 134 dpi on the CT films. The cameras produce image noise comparable to CT with low window settings and reduced local resolution. We expect similar results for CT with soft tissue windows or for MRT of the skull. Conventional radiographs containing high local resolution, wide grey scale and low image noise would presumably make higher demands on methods of digitization.

Computers↗

[Dynamic computerized tomography of the bone marrow of normal and pathologic vertebrae].

PURPOSE: The contrast medium dynamics of normal and abnormal bone marrow was examined by CT. MATERIAL AND METHOD: Standardised sections of lumbar vertebrae were obtained after intravenous injection of 80 ml Ultravist 370 and time-density curves of the marrow spaces were calculated in 38 patients. RESULTS: Time-density curves of patients with normal bone marrow differed significantly from those with proliferative bone marrow diseases in respect of maximal density and uptake at 120 and 240 seconds. Patients treated by radiation showed reduced uptake. CONCLUSION: Variations in the time-density curves between normal and abnormal bone marrow provided evidence of different perfusion and uptake of the contrast medium in the extracellular space of the bone marrow. Further investigation will be necessary to determine whether dynamic CT is able to document the effect of radiotherapy or chemotherapy on malignant bone marrow infiltration.

Adenocarcinoma↗

[Use of Ga-67 SPECT in patients with malignant lymphoma after primary chemotherapy for further treatment planning: comparison with spiral CT].

PURPOSE: To compare the diagnostic value of gallium scintigraphy using a SPECT technique with spiral CT for evaluating activity following chemotherapy in patients with malignant lymphoma and to determine treatment options. MATERIAL AND METHOD: The results of gallium scintigraphy in 28 patients with malignant lymphoma (19 Hodgkin's disease, 9 high grade non-Hodgkin's lymphoma) following curative treatment were compared with the CT morphology in relation to inactive regions and residual masses. RESULTS: Ga-67-SPECT proved superior to CT for evaluating the activity in 85 initially involved nodes (sensitivity 94.4% against 83.3%; specificity 100% against 92.5%). It was, however, inferior for demonstrating organ involvement in 28 instances. In seven patients with residual masses, Ga-67-SPECT directly affected staging and further therapy. CONCLUSION: The increasing use of secondary treatment schemes for curative purposes makes Ga-67-SPECT a suitable method for the early recognition of residual activity in Hodgkin's disease and high grade non-Hodgkin's lymphoma.

Adult↗

["Second opinion" in online radiology via Internet: report on implementation and analysis of reliability of findings in sectional images].

Numerous medical on-line services have already been established in the world-wide internet. In connection with the Information service TELESCAN, sponsored by the EU, a pilot project has been initiated which offers a radiological "second opinion" via the transmission of radiological findings and images that have been previously rendered anonymous. In addition to a description of the basic implementation, tests of the diagnostic certainty of the transmitted cranial computed tomographs have been performed. The CT images were digitized with a document camera, transmitted over the Internet, and then evaluated on the receiver's monitor. Both the transfer of originally generated digital image files (in ACR-NEMA or DICOM) as well as graphic files after digitization of X-ray films, for example by a document camera, is possible via electronic post (e-mail). Visualization by the receiver requires the use of current proprietary software for special medical image formats, while standard graphic formats such as GIFF or JPEG can be visualized with the usual Internet software. In an ROC analysis, 56 individual images of cranial computed tomographs, half with pathological findings such as space-occupying lesions, infarcts, or brain edema, were tested with regard to the diagnostic certainty after digitization and transmission. In comparison with the original film findings, there was a slight but statistically not significant reduction in diagnostic certainty of the images evaluated on screen after transfer via the Internet. We believe that this result is due to the low local resolution, low dynamic range, the high image noise and of CT arising from the window technique. The same parameters are probably valid for MRI. The result cannot be applied to conventional radiography including mammography because, in comparison to the mentioned image techniques, their local resolution is high and image noise is considerably lower.

Computer Communication Networks↗

Calcified brain metastases from ovarian carcinoma.

A case of calcified brain metastases from ovarian carcinoma is reported. Lesions developing during chemotherapy were thought on Ct to be parasitic and, to avoid dissemination of pathogens, biopsy was postponed. When neurological deficits progressed, MRI showed perifocal oedema and contrast enhancement. It also showed a new noncalcified focus which was biopsied, proving to be a metastasis.

Brain Neoplasms↗

[Teleradiology: use of multimedia PC for access to electronic patient records and teleconsultation].

A PC-platform is presented using internet technology on Ethernet (local) or ISDN (external) for access to digital hospital infrastructures comprising electronic multimedia patient records integrating information systems of all clinical departments. In addition, a videoconferencing system is implemented for teleconsulting, and a document camera allows transmission of analogue data. In combination with the multimedia-PC. Ethernet as well as ISDN offer satisfying performance for transmission of medical data including images. In 20 cases, visualisation of the electronic patient record, an average CT with report and 58 GIFF Images', or transfer of an ACR-NEMA file from CT, took seconds (Ethernet) or up to 3.5 minutes (ISDN - 58 CT images and report).

Computer Communication Networks↗

Telemedicine in rural areas. Experience with medical desktop-conferencing via satellite.

Cooperation between physicians in hospitals in rural areas can be assisted by desktop-conferencing using a satellite link. For six weeks, medical desktop-conferencing was tested during daily clinical conferences between the Virchow-Klinikum, Berlin, and the Medical Academy, Wroclaw. The communications link was provided by the German Telekom satellite system MCS, which allowed temporary connections to be established on demand by manual dialling. Standard hardware and software were used for videoconferencing, as well as software for medical communication developed in the BERMED project. Digital data, such as computed tomography or magnetic resonance images, were transmitted by a digital data channel in parallel to the transmission of analogue video and audio signals. For conferences involving large groups of people, hardware modifications were required. These included the installation of a video projector, adaptation of the audio system with improved echo cancellation, and installation of extra microphones. Learning to use an unfamiliar communication medium proved to be uncomplicated for the participating physicians.

Germany↗

[Megadolichobasilar artery as a rare cause of hydrocephalus internus: synopsis of modern imaging methods].

Megadolichobasilarartery (MDB), i.e. the widened, elongated and tortuous course of the basilar artery, has been the topic of numerous publications; about 350 cases have been reported world-wide. It can cause many symptoms; isolated or combined cranial nerve lesions and ischemic or hemorrhagic changes are the most frequent. A hydrocephalus internus is a rare occurrence and many patients do not exhibit any symptoms. To date, angiography, computed tomography, and to an increasing extent magnetic resonance imaging (MRI) are the principal methods for diagnosis of MDB. Angiographic-like representations with CT and MRI are further developments which represent an alternative to angiography. With the help of special MRI sequences, furthermore, non-invasive CSF flow measurements for the etiologic evaluation of a hydrocephalus can be performed. For the example of a patient with MDB and hydrocephalus internus, the possibilities of modern imaging techniques are presented and discussed.

Basilar Artery↗

[Technique and economics of first worldwide roentgen conference via public phone lines with the Medical Desktop-Conference and Integrated Services Digital Network].

The introduction of the world's first Medical Desktop-Conference via public phone lines (ISDN-S2M) in spring 1994 for the weekly discussion of radiological findings with 25 orthopedic surgeons has proved the effectiveness of this system developed by the project BERMED. The use of standard hard- and software as well as ISDN are the most important factors to keep the system costs low. Technical advantages can be seen in the immediate, loss-free transmission of image and other patient-related data and in the integration of digital archives. Medical advantages are the 24-hour-availability of the radiologist and quality-control of the radiologists work. Practitioners and external hospitals can be tied closely to radiological service centers by using ISDNetwork.

Computer Communication Networks↗

Thermoablation of liver metastases: efficacy of temporary celiac plexus block.

PURPOSE: To determine the efficacy of celiac plexus block during thermoablation of liver metastases. METHODS: Fifty-five consecutive patients underwent thermoablation therapy of liver tumors by laser-induced thermotherapy. Twenty-nine patients received a temporary celiac plexus block, 26 patients acted as control group. In both groups fentanyl and midazolam were administered intravenously upon request of the patient. The duration of the intervention, consumption of opiates, and individual pain sensations were documented. RESULTS: No complications resulting from the celiac plexus block were recorded. Celiac plexus block significantly reduced the amount of pain medication used during thermoablation therapy of liver tumors (with block, 2.45 mug fentanyl per kg body weight; without block, 3.58 mug fentanyl per kg body weight, p < 0.05; midazolam consumption was not reduced) in patients with metastases < or = 5 mm from the liver capsule. For metastases farther away from the capsule no significant differences in opiate consumption were seen. Celiac plexus block reduced the time for thermoablation significantly (178 min versus 147 min, p < 0.05) no matter how far the metastases were from the liver capsule. Average time needed to set the block was 12 min (range 9-15 min); additional costs for the block were marginal. As expected (as pain medications were given according to individual patients' needs) pain indices did not differ significantly between the two groups. CONCLUSION: In patients with liver metastases < or = 5 mm from the liver capsule, celiac plexus block reduces the amount of opiates necessary, simplifying patient monitoring. In addition celiac plexus block reduces intervention time, with positive effects on overall workflow for all patients.

Analgesics, Opioid↗

Use of semiflexible applicators for radiofrequency ablation of liver tumors.

PURPOSE: To evaluate the feasibility and potential advantages of the radiofrequency ablation of liver tumors using new MRI-compatible semiflexible applicators in a closed-bore high-field MRI scanner. METHODS: We treated 8 patients with 12 malignant liver tumors of different origin (5 colorectal carcinoma, 2 cholangiocellular carcinoma, 1 breast cancer) under MRI guidance. Radiofrequency ablation (RFA) was performed using 5 cm Rita Starburst Semi-Flex applicators (Rita Medical Systems, Milwaukee, WI, USA) which are suitable for MR- and CT-guided interventions and a 150 W RF generator. All interventions were performed in a closed-bore 1.5 T high-field MRI scanner for MRI-guided RFA using fast T1-weighted gradient echo sequences and T2-weighted ultra-turbo spin echo sequences. Control and follow-up MRI examinations were performed on the next day, at 6 weeks, and every 3 months after RFA. Control MRI were performed as double-contrast MRI examinations (enhancement with iron oxide and gadopentetate dimeglumine). All interventions were performed with the patient under local anesthesia and analgo-sedation. RESULTS: The mean diameter of the treated hepatic tumors was 2.4 cm (+/-0.6 cm, range 1.0-3.2 cm). The mean diameter of induced necrosis was 3.1 cm (+/-0.4 cm). We achieved complete ablation in all patients. Follow-up examinations over a duration of 7 months (+/-1.3 months, range 4-9 month) showed a local control rate of 100% in this group of patients. All interventions were performed without major complications; only 2 subcapsular hematomas were documented. CONCLUSION: RFA of liver tumors using semiflexible applicators in closed-bore 1.5 T scanner systems is feasible. These applicators might simplify the RFA of liver tumors under MRI control. The stiff distal part of the applicator facilitates its repositioning.

Aged↗

Percutaneous transjugular direct porto-caval shunt in patients with Budd-Chiari syndrome.

The purpose of the study was to evaluate the feasibility and effectiveness of direct porto-caval shunts in patients with Budd-Chiari syndrome (BCS) in whom there is no access to the hepatic veins during transjugular intrahepatic portosystemic shunt (TIPSS). We included six consecutive patients with fulminant/acute Budd-Chiari syndrome (mean age: 35 years) in whom a conventional TIPSS was not possible due to inaccessible hepatic veins. We performed a direct porto-caval shunt via a transhepatic approach. Patients were followed up by means of clinical examination, laboratory investigations, and Doppler ultrasound. TIPSS implantation from the inferior vena cava (IVC) was successful in all six patients (100%). The median transhepatic shunt length was 9 cm (8-10 cm). No procedure-related complications were observed in our patients. Early shunt occlusion occurred in three out of six patients (50%). In all three of these patients, the stent used to stabilize the shunt ended 1-2 cm before reaching the IVC. All occlusions were successfully recanalized. One of these patients developed recurrent early shunt as well as mesenteric and splenic vein occlusions. She died 7 days after TIPSS placement due to an unmanageable coagulation disorder. The remaining five patients were followed up by planned clinical examination and laboratory investigations (mean follow-up time was 15 months; patient 1 was followed up for 13 months, patient 2 for 14 months, patient 3 for 15 months, and patients 4 and 5 for 16 months) and all displayed a complete and durable resolution of liver failure and ascites without reintervention. In patients with acute liver failure originating from BCS and inaccessible hepatic veins, a direct transhepatic porto-caval shunt can be performed safely and effectively under ultrasound guidance. Future studies in larger patient groups should investigate if the patency of transcaval TIPSS with long transhepatic shunt segments is similar compared to conventional TIPSS via the hepatic vein.

Adult↗

Shortcomings of low-cost imaging systems for viewing computed radiographs.

OBJECTIVE: To assess potential advantages of a new PC-based viewing tool featuring image post-processing for viewing computed radiographs on low-cost hardware (PC) with a common display card and color monitor, and to evaluate the effect of using color versus monochrome monitors. MATERIALS AND METHODS: Computed radiographs of a statistical phantom were viewed on a PC, with and without post-processing (spatial frequency and contrast processing), employing a monochrome or a color monitor. Findings were compared with the viewing on a radiological Workstation and evaluated with ROC analysis. RESULTS: Image post-processing improved the perception of low-contrast details significantly irrespective of the monitor used. No significant difference in perception was observed between monochrome and color monitors. The review at the radiological Workstation was superior to the review done using the PC with image processing. CONCLUSION: Lower quality hardware (graphic card and monitor) used in low cost PCs negatively affects perception of low-contrast details in computed radiographs. In this situation, it is highly recommended to use spatial frequency and contrast processing. No significant quality gain has been observed for the high-end monochrome monitor compared to the color display. However, the color monitor was affected stronger by high ambient illumination.

Humans↗