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Biomedical subjects

J Revuz

Publications and source records attributed to J Revuz.

At least 235 records · Page 13Linked to original sources
PubMed1991

Cogan's syndrome. An unusual etiology of urticarial vasculitis.

We report the case of an 18-year-old black woman with urticarial vasculitis, vestibuloauditory dysfunction and superficial keratitis. Oral steroid therapy was effective in reducing most clinical manifestations with high-dosage dependency. However, only intravenous pulses of methylprednisolone allowed slight improvement of hearing. In this case, we emphasize urticarial vasculitis as a new manifestation of atypical Cogan's syndrome. A significant titer of Chalmydia trachomatis antibodies was found in our patient: their role in the pathogenesis of Cogan's syndrome is discussed.

Adolescent↗
PubMed1991

[Acne fulminans triggered by isotretinoin therapy].

An 18-year old male patients with tetracycline-resistant acne vulgaris was prescribed isotretinoin in daily doses of 0.5 mg/kg. Ten days later, he developed an acute episode of acne fulminans which was regressive. Subsequently, two attempts were made at reintroducing isotretinoin; the first one was followed by a new episode of acne fulminans and the second one, by ordinary myalgias, while the patient was still under corticosteroid therapy. A search in the literature yielded 14 cases of acne fulminans that had possibly been induced by isotretinoin. Doses and intervals between medication and acute manifestations varied, and the responsibility of isotretinoin was seldom demonstrated. Associations with erythema nodosum myalgias and arthralgias have been described. This rare adverse effect of isotretinoin therapy must be known. Its course and treatment are not different from those of ordinary acne fulminans.

Acne Vulgaris↗
PubMed1991

[Seborrheic dermatitis and cancer of the upper respiratory and digestive tracts].

Seborrheic dermatitis (SD) is frequent in adults. Its aetiology is unknown, and the alleged causative effect of Pityrosporum-type yeasts is strongly controverted. Nutritional, genetic and neuropsychological factors may play a part in its occurrence. The responsibility of immunological factors has recently been illustrated by the high prevalence of SD in patients with acquired immunodeficiency syndrome. We found a high frequency of SD in patients under treatment for carcinomas of the upper respiratory and digestive tracts (URDT), and in order to confirm this finding we carried out a prospective case-control epidemiological study. Since most patients with URDT carcinoma are heavy drinkers and smokers, we divided our controls into two groups: chronic alcoholics without cancer (Group B) and patients with non-URDT cancers. At the time of admission, all patients were examined by the same physician, and SD was diagnosed on clinical grounds. Cases (Group A) comprised 50 patients (48 men, 2 women; mean age 56 years) with URDT carcinoma. All were alcohol and tobacco addicts. Thirty-six of these patients had undergone surgery for their cancer, and among these 19 had received radiotherapy, 8 chemotherapy and 18 both chemo- and radiotherapy. The first control group (Group B) also comprised 50 patients, all male, with a mean age of 59 years, who had been admitted for diseases due to alcoholism but showed no evidence of cancer. The second control group (Group C) consisted of 50 male patients (mean age 69 years) whose cancer was not an URDT carcinoma.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗