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Biomedical subjects

J Reviron

Publications and source records attributed to J Reviron.

At least 37 records · Page 2Linked to original sources
PubMed1983

Study of blood group B antigen with a specific monoclonal antibody (anti-B, b-183).

A murine anti-B monoclonal antibody was obtained by the hybridoma technique. This antibody called anti-B (b-183) is of IgM nature; it is capable of agglutinating normal B, B3, Bx, cis AB and some acquired B red cells. Its association constant is 1.1 X 10(8) l/mol, and appears high compared to those of the monoclonal anti-A. This monoclonal anti-B was used to determine the number of B sites on B3 and Bx red cells.

ABO Blood-Group System↗
PubMed1982

[Production of an anti-digitalin monoclonal antibody (author's transl)].

Anti-digitalin monoclonal antibodies were obtained by hybridization of lymphoid cells from mice immunized with the drug and the 8653 myeloma cells from BALB/c Mice. Two of these antibodies were submitted to immunochemical analysis which revealed that they belonged to IgM and IgGl classes, and the high affinity of one of them (1,2 x 10(9) M(-1)). The availability os such antibodies opens new perspectives for the treatment of digitalin intoxication and the possibility of establishing a standardized radioimmunoassay.

Animals↗
PubMed1981

Thermodynamic and immunological properties of a monoclonal antibody to human blood group A.

A murine anti-A monoclonal antibody was obtained by the hybridoma technique. This antibody, of an IgM nature, is capable of agglutinating A1, A2 and A3 red blood cells. Thermodynamic study confirmed its monoclonal character; its association constant is 1,6 10(6) l/mole. The enthalpy change of the antigen/antibody reaction is nul which indicates the absence of the role of temperature on antibody fixation. This weak affinity makes it necessary to concentrate the supernatant so as to enable use of these reagents under the same conditions as those used at present.

ABO Blood-Group System↗
PubMed1979

[Technics and applications of transfer factor (author's transl)].

Transfer factor is produced by dialysis of repeatedly frozen and thawed pooled buffy coats of healthy blood donors. However, "specific Transfer Factor" of bacteriological or mycological type, prepared from hyperimmunized donors would be more effective for restoring cellular immunity.

Hematologic Diseases↗
PubMed1975

[Somatic segregation and Fanconi's anemia].

The chromosome marrow cells of two patients suffering from Fanconi's anemia were studied. Abnormal clones were found, pseudodiploid in one case, aneuploid in another. The analysis of these clones showed that somatic segregation occurred, resulting in partial homozygosity.

Adolescent↗