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Biomedical subjects

J Renaud

Publications and source records attributed to J Renaud.

49 records · Page 3Linked to original sources
PubMedDate not supplied

[Antigenic analysis of cheese mites with view to a study of cheese-makers' illness (author's transl)].

"Somatic" and "metabolic" antigens prepared from A. farinae and T. casei mites in Auvergne cheese were used for experimental immunisation: the hyper-immune serums obtained permitted 11 to 21 precipitant systems to be distinguished. An enzymatic activity could be identified on certain arcs. Research into antigenic communities showed the existence of 1 to 3 arcs common to the mite antigens, but none with the antigens obtained from the Penicillium cyclopium and Mucor fuscus moulds accompanying the mites. The results obtained thus facilitate an epidemiological investigation among the cheesemakers.

Antigens↗
PubMedDate not supplied

[Nuclear proteins of stimulated lymphocytes (author's transl)].

Lymphocytes activated by phytohaemagglutinin (PHA) change from a resting state (GO) to an actively growing one (G1). To investigate the role of growth regulatory protein in this process we have determined the patterns of synthesis of acidic (non-histone, NHCP) and basic (histone) nuclear chromatin proteins, and of cytoplasmic proteins during PHA activation of human lymphocytes, Protein fractions isolated from a mixture of stimulated (pulse-labelled with 14C leucine) and unstimulated (labelled with 3H-leucine) lymphocytes were separated on SDS-polyacrylamide gel electrophoresis and the ratio of 14C/3H determined on 1 mm gel slices. Several peaks of increased synthesis of specific peptides are detected in all fractions within 12 h of activation. When activation is blocked by an amino acid deficiency, the pattern of label upon release of the inhibition by addition of the missing amino acid is different from that of uninhibited lymphcytes.

Chromosomal Proteins, Non-Histone↗