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Biomedical subjects

J Reiner

Publications and source records attributed to J Reiner.

At least 55 records · Page 3Linked to original sources
PubMed1983

The identification of urinary bile alcohols by gas chromatography-mass spectrometry in patients with liver disease and in healthy individuals.

The neutral steroid fractions in the urine of eleven patients suffering from various forms of liver disease with cholestasis and of ten healthy individuals were studied by glass capillary gas chromatography-mass spectrometry. The steroid conjugates in urine were enzymatically solvolysed, the liberated steroids extracted and transformed into the trimethylsilylether for measurements. The excretion rates of androstane and pregnane metabolites of patients with liver disease were far lower than those of healthy persons. The main compounds in the urine of the former were the bile alcohols 27 - nor - 3 alpha, 7 alpha, 12 alpha, 24 xi, 25 xi - pentahydroxy - 5 beta - cholestane and 3 alpha, 7 alpha, 12 alpha, 25 xi, 26 - pentahydroxy - 5 beta - cholestane. Our data suggest a correlation between the excretion rates of these bile alcohols and the serum levels of bilirubin. While the excretion rate of the two bile alcohols in the urine of healthy individuals was approximately 0.24 mg/24 h (0.6 mumol/24 h) a patient with a serum bilirubin of 841 mumol/l excreted 4 mg/24 h (9 mumol/24 h). The accumulation of bile alcohols described in this study possibly indicates alternative pathways of cholic acid formation in liver disease.

Adult↗
PubMed1979

[Applications of novel stereomicroscopic spectacles in ophthalmic surgery (author's transl)].

The previous magnifying spectacles and telescopic spectacles designed on the principle of the Galilean telescope have a magnification of only 2.5 x to 3 x for good image quality. New magnifying systems from Zeiss based on the Kepler telescope principle offer 3 x to 8 x magnification and thus cover the range between magnifying spectacles and operation microscopes and even come into the latter range. The following versions are available for ocular surgery: 1. Mounted on headband. 2. Fastened to the frame in front of the lenses. 3. Cemented into drilled holes in the lenses with additional horizontal connection of the magnifying systems. 4. Cemented into drilled holes in the lenses without horizontal connection. These versions offer different advantages and are selected according to the particular field of application and the refraction of the surgeon. With these compact and easily transportable stereomicroscopic systems the surgeon has complete freedom of movement being able to select the most convenient position at any stage of the examination or operation. Further applications of such stereomicroscopic spectacles beyond the field of ophthalmic surgery are mentioned.

Eye Diseases↗
PubMed1978

[Urine steroid profiles of hirsute women (author's transl)].

Steroid profiles of women suffering from idiopathic hirsutism show in more than 50% of the cases of 10--100 fold increase in the excretion of dehydroepiandrosterone (DHEA) compared with normal values. The excretion of DHEA was reduced much more than that of other 17-ketosteroids if the adrenals (NNR) were suppressed by dexamethasone (DXM). Within one week they reached values at the compound noise level of the gas chromatograms. If the ovaries were stimulated with human chorionic gonadotropin during continued suppression of the NNR with DXM no increase of DHEA could be detected.

17-Ketosteroids↗
PubMed1978

[The best spectacles for vehicle drivers (author's transl)].

Spectacles worn by vehicle drivers should fulfil the demands set down by DIN 58 216 standards and should furthermore be constructed in such a manner that the binocular field of vision is impaired as little as possible. In this connection, the nasal parts of the frame are particularly important. The external and internal rear-view mirrors of automobiles should be positioned within the binocular field of vision.

Automobile Driving↗
PubMed1977

[New spectacle lenses with variable progressive refractive power (author's transl)].

Spectacle lenses with variable optic power are indeed no replacement but are an interesting addition to the group of visual aids for correcting presbyopic patients. Since the first commericial lenses of this kind appeared in the year 1959, further sorts of glass with variable properties have been developed. These were evaluated and compared with each other.

Eyeglasses↗
PubMed1977

[A new apparatus for testing binocular vision (author's transl)].

The Optometer can be used in a binocular manner if the loupe-lens is replaced by a concave mirror of appropriate size and form. The concave mirror or the plane mirror connected to it can be partially transparent. With an appropriate arrangement of these elements the test field can be seen in free space. The image can be adjusted from infinity to 35 cm by displacement of the test object. Choice of the test object makes possible testing the stereoscopic vision under natural conditions. Other test objects can be used to test further functions of the eyes-monocular, binocular or separately.

Optometry↗
PubMed1977

[Binocular fusion of anamorphotic distorted images (author's trnasl)].

A astigmatic eye corrected with a spectacle lens results in an anamorphotic optical system which gives a distorted image of the environment on the retina. Fusion disturbances were ppresent especially in oblique astigmatism. The explanation for this can come either from a displacement of the image points on the retina or from the prismatic side effects of the spectacle lenses.

Astigmatism↗
PubMed1976

[A new magnifying visual instrument for ophthalmic surgery (author's transl)].

A binocular loupe on the principle of the prismatic telescope, small in size and light in weight, and which can be firmly by straps to the head of the doctor, has been developed for use in operative ophthalmology, for the clinical visit, consultation and in the office. Its optic properties greatest possible distance from the work which can be varied with additional lenses, variable magnification even into the region of the smallest biomicroscopes with a relatively large angle of vision, good mobility with regard to the object of vision with unchanged adjustment, simultaneous possibility of using semispectacles for presbyopia and easy swinging of the instrument out of and into the line of vision with one hand movement make this instrument very appropriate for the reasons for which it was developed and makes possible also - especially in the surgery of injured eyes, exact observation and assessment of the eye and performance of operations where no operating microscope is present with much greater magnification as that obtained with a customary loupe. This instrument occupies the spare between the possibilities of use of the loupe and the biomicroscope and can in addition be used in the boundary areas of use of the other instruments with great advantage.

Eye Diseases↗