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Biomedical subjects

J Reichman

Publications and source records attributed to J Reichman.

25 records · Page 2Linked to original sources

Multiple carcinomas following therapy for Hodgkin disease.

A 52-year-old man developed synchronous squamous-cell carcinoma of the larynx and middle one-third of the esophagus following treatment of Hodgkin disease. This patient fell into the subgroup of patients treated by intensive radiation therapy followed by intensive chemotherapy. The link between the therapy and subsequent carcinoma is suggestive. Long-term follow-up care of patients with Hodgkin disease demands continuing evaluation of this possible complication.

Antineoplastic Agents↗

Secondary cervical perforation by the Copper-T intrauterine device.

Five cases of cervical perforation have been observed in women with a Copper-T IUCD, over a period of 5 yr. In all cases, the distal end of the stem (vertical limb) of the T had perforated through the cervical wall into one of the fornices of the vagina. Only 2 cases had symptoms leading to the discovery of the device, while the other 3 were discovered accidentally or on routine examination.

Adult↗

Immediate postabortion intrauterine contraception in nulliparous adolescents.

Immediate postabortion insertion of an intrauterine device (IUD) was performed in 162 nulliparous adolescents. No insertion failures occurred. Twelve-month continuation rates were 86.6% for the Copper-7 IUD, 75.4% for the Copper-T device and 48.2% for the Lippes loop. Overall complications were greater for the Lippes loop than for the other two devices. The results suggest that immediate postabortion insertion should be considered for poorly motivated or uneducated adolescent girls who have already failed in contraception and require abortion.

Abortion, Induced↗

Serotonin inhibition and sleep.

Methysergide a clinically used blocker of serotonin receptors, was given for 48 hr to 11 normal adults, at a dose of 8 mg per 24 hr. Total REM sleep time was decreased, although total sleep time was unchanged. Stage 4 decreased and stage 3 increased, while total slow wave sleep remained constant. There was a tendency toward a decrease in the number of intact sleep cycles. The relationship of these data to published reports on p-chlorophenylalanine is discussed.

Administration, Oral↗