[Experimental degeneration of the central nervous system: study of serial sections, counterstained after silver impregnation and clearing treatment].
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Biomedical subjects
Publications and source records attributed to J Raymond.
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Glutamate solutions of either 50 mM applied on the membranous labyrinth or 1 mM perfused into the lateral canal in cats increased spontaneous and stimulus-evoked activity of vestibular neurons. Kainic acid (10(-4) M) perfused into the labyrinth produced a depolarizing action on vestibular afferents. These results indicate that glutamate could be an excitatory neurotransmitter at the synapse between vestibular hair cells and afferent nerve fibers in the cat.
A tritiated amino acid tracing method was used to test the hypothesis that a unilateral group of vestibular efferent neurons of the brain stem may present different innervation patterns to the sensory vestibular epithelia of the ipsi- and contralateral labyrinths. Densitometric analysis of labeled efferent endings suggested a heterogeneity of the efferent projections issuing from a unilateral predominated in the maculae utriculi and cristae ampullares of the semicircular canals. These findings are discussed as a function of other data related to efferent vestibular control.
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