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J Rassow

Publications and source records attributed to J Rassow.

At least 91 records · Page 5Linked to original sources

Scaling relative neutron depth-dose distributions from one phantom material to another: a comparison of experimental and theoretical results.

To correct percentage depth-dose data from one phantom material to another, experimental and theoretical scaling factors (SF) are compared for different neutron beam qualities. Differences of up to 10% were observed for different phantom materials relative to water. The ratio SF/rho was plotted as a function of H concentration by mass where rho is the mass density of the phantom material. A nearly linear relationship resulted at all energies for the theoretical scaling factors, while, for the experimental points, important deviations appeared at high energies for materials with relatively low H and high C concentrations. It can be shown that a single linear relationship for all compounds composed of H, C and O can only be valid if the ratio of total cross sections of carbon to oxygen is equal to 3/4. Experimental scaling factors will be more accurate than calculated values because of the uncertainty in the average total cross sections. If these factors for tissue equivalent (TE) liquid relative to water are converted to those of ICRU muscle by correcting to a mass density of 1.04 g cm-3, then the scaling factors are, within experimental uncertainty, equal to one.

Fast Neutrons↗

[Principle of the 2-peak thermoluminescent dosimetry method for the simultaneous determination of neutron-gamma energy doses in mixed neutron-photon radiation fields].

The LET dependence of the response of different glow-peaks of CaF2 : Tm (TLD-300) detectors can be used for separate simultaneous determination of neutron and gamma-ray absorbed doses in mixed neutron-photon radiation fields. The principle the pre-conditions of this "two-peak TLD method" are explained using experimental results with d(14) + Be neutrons (EN = 5,8 MeV).

Fast Neutrons↗

Radiotherapy of soft tissue sarcomas with neutrons or a neutron boost.

A cooperative trial of neutron therapy for soft tissue sarcomas was started in 1978. 112 unselected and not previously irradiated patients (62% T3 tumours, 35% recurrent tumours) were treated up to June 1982 with neutrons alone. An analysis of these cases with a mean follow-up period of 22 months (range 12 to 45 months) is given in this report. Very preliminary results are presented for 60 patients treated with a neutron boost only. These showed a substantially lower complication rate. The major results of this phase II trial are: The survival rate of 3.5 years was strongly dependent on the stage of the tumour; for 8 patients with T1 tumours it was 100%, for 35 patients with T2 tumours, 77%, and for 69 patients with T3 tumours, 45%. The survival rate at 3.5 years was strongly dependent on surgery before the beginning of radiotherapy; for 54 patients after surgery without clinical evidence of residual tumour it was 73%, for 58 patients with inoperable primary or recurrent tumour, 47%. The survival rate of 31 patients with recurrence after neutron therapy was only 36%. The overall rate of serious complications was 28.6% after neutron therapy, but only 5% after neutron boost therapy (mean follow-up period: 12 months, range 5 to 48 months).

Follow-Up Studies↗

Dosimetrical verification of calculated total and gamma absorbed dose distributions DT, respectively DG, for fast neutron therapy.

The physical part of treatment planning for neutron therapy is highly important but quite more complicated than for photons and electrons due to the necessity of separation of total and gamma absorbed dose distributions (DT and DG). Therefore, dosimetrical verifications of dose distributions of complex treatment plans are very rare, and the experimental difficulties are enormous. A method using TLD-300 (CaF2: Tm) detectors is described with the ability to provide from each detector's readings both DT and DG using the different LET dependence of the main glow-curve peaks. The principle of an on-line computer program is given for an automatic mathematical glow-curve analysis which is necessary to achieve the accuracy of about +/- 5% (DT) and +/- 10% (DG) in single fixed fields. Dosimetrically relevant features of the TLD-300 method are discussed. Examples of dosimetrical verifications of calculated dose distributions (DT and DG) for a treatment with one single fixed field, with two wedge filter fields and with a rotational field with d(14)+Be neutrons are shown. Deviations exceeding significantly the uncertainties above are found only in the case of the wedge filter treatment for the absolute (quite less for the relative) values of the DG dose distribution. Probable reasons are mostly the reduced contribution of scattered radiation for phantom sizes, which laterally scarcely exceed the useful beam, and slight neutron energy spectrum changes by the wedge filter.

Dose-Response Relationship, Radiation↗

[Responsibility, status and role of the medical physicist in the Federal Republic of Germany (author's transl)].

Pursuant to the regulations of the Roentgenverordnung (decree about X-ray examination and therapy), the Strahlenschutzverordnung (decree about radiological protection), and the Richtlinie Strahlenschutz in der Medizin (guide-line for radiological protection in medical practice), the responsible collaboration of a physicist on the diagnostic and therapeutic application of ionizing radiation is prescribed by law or, at least, seems reasonable with regard to the protection of the patient. This is why the authors describe the tasks and necessary qualifications of the physicist (competence as to radiological protection and professional admission) which are prescribed by law in the Federal Republic of Germany or which are desirable with respect to the performance of radioprotective measures during the application of ionizing radiation in medical practice. Furthermore, the authors summarize the results of a recently made inquiry about the state (e.g. education, professional experience, participation in medical care) and the role of the medical physicist (e.g. institutionalization of Medical Physics, educational work).

Germany, West↗

A small-scale neutron dosimetry intercomparison between Essen, Amsterdam and Edinburgh.

An intercomparison of neutron dose measurements was made at Essen by visiting groups from Amsterdam and Edinburgh to compare measurements of the neutron and photon absorbed doses in a phantom in the neutron beam. An intercomparison of the photon calibration of the tissue-equivalent chambers was also made. Differences in the measurements of total absorbed dose in the neutron beam of up to 4.7% were observed. These were consistent with the observed differences in the photon calibrations. A summary is given of the different calibration methods used by each group. Greater discrepancies (up to 18%) were seen in the measurement of the photon contribution to the absorbed dose in the neutron beam and these were in part due to insufficient shielding of the GM counter from thermal neutrons.

Germany, West↗

[Contribution to deep electron pendulous therapy. VIII. Communication: concerning the problem of diverging contours in telecentric electron pendulous irradiation using the electron energies 10 MeV and 20 MeV (author's transl)].

The mode of correction of the isodose curves from telecentric electron pendulous technique using a constant patient radius rp = 30 cm (Isodosenatlas, Siemens, 1973) is represented with regard to its application in patients with diverging surface contours. Correction is possible by two different methods: 1st by experimental determination of an air gap factor for the shift of isodoses, and 2nd by two factors depending on the focus-skin distance and on the angle of incidence of the electron beam. Determination of the factors is performed either by means of fixed fields measured by vertical and at oblique incidence of the beam and a depth dose distribution measured at the central axis, with oblique incidence of the electrons.

Electrons↗

Proposal for a practical dose calculation scheme for neutron irradiations.

Dose calculations for neutron therapy irradiations should be based on the dosimetrically best accessible parameters "total absorbed Dose Dt" and "gamma ray absorbed dose Dgamma". By adequate standardization it should be possible, that only one single reference parameter contains all deviations of calibration, while a table of relative factors, only once to be determined, gives all long-term constant dependencies for all field sizes and phantom depths. A standardization is proposed for the irradiation technique with fixed fields at a constant focus-skin distance, giving rise to especially simple equations for the absorbed doses Dt and Dgamma. It is as well easy to get by these doses and mean relative biological effectivenesses rn for neutrons and rgamma for gamma rays the "total effective absorbed dose De", being an opportune quantity for the biologically weighted absorbed dose. The practical application of equations and tables is demonstrated for an opposing field irradiation as example. Adequately standardized "reference tissue air ratios" and corresponding equations are given for isocentric fixed or rotating beam irradiations and used for the example of a dose calculation within a phantom at the isocentre.

Humans↗

On a simple method for routine check of the constancy of radiation quality of bremsstrahlung emitted by therapeutic particle accelerators.

The constancy of radiation quality of therapeutically employed particle accelerators has to be checked at weekly intervals. Any change in radiation quality may have considerable therapeutic effects owing to its influence on dose distribution. It can be recommended to make measurements instead of, or in addition to, the axial reference-point measurement at 5 and 15 cm depth in the phantom, at 5 cm depth in the beam axis and at a reference-point about 1 cm within the geometric edge of the field, for checking the constancy of the radiation quality of bremsstrahlung. Only then, if routine checks carried out for the axial and the lateral reference-point dose ratios do not show any deviations greater than e.g. +/- 2%, radiation quality is deemed to have remained sufficiently constant for radiotherapeutical applications.

Radiotherapy, High-Energy↗

[Measurements of bone mineral concentration ("hydroxylapatite-volume values") and of bone density in vitro and in vivo with a densitometric method using beams of two different energies (author's transl)].

The densitometric method of Rassow-Strüter (1969) using beams of two energies permits separate estimations of bone mineral and connective tissue concentrations in bone; their sum indicates bone density. The value of the method has been examined and the early results of in-vitro and in-vivo measurements are quoted. The former were obtained from pairs of macerated calcanei and vertebral bodies embedded in resin blocks. The in-vivo estimations were concerned with obtaining normal values in healthy children aged four to fifteen years and adults aged 18 to 54 years. Standard deviation, obtained from measurements of four different points of both calcanei in adults was KM 12% for Hydroxylapatite-volume values, and for bone density 14%. The average value for KM for the whole group is 198 mg/cm3 with 17% standard deviation of the single measurements compared with the average. The following-up measurements for children with renal disease do not yet allow final conclusions about the correlation of the clinical aspects of case to the measured bone parameters and their value as independent criteria. For 16 nursing mothers a significantly lower average HA volume value KM = 149 mg/cm3 +/- 21% was found.

Absorptiometry, Photon↗

Procedure for field axes measurement, beam indication adjustment, and figure of convergence determination within performance tests for radiation therapy equipment.

A routine measuring procedure for the verification of radiation field axes and figure of convergence within a spatial resolution of +/- 0.5 mm is described. Measurements are done in two parallel planes in a certain distance before and behind the presumed isocentre. The used test arrangement permits rapid check and controlled adjustment of the alignment of beam or isocentre indicating devices for all isocentic radiation therapy equipment.

Mathematics↗