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Biomedical subjects

J Rai

Publications and source records attributed to J Rai.

At least 37 records · Page 2Linked to original sources

Magnesium inhibition of carbachol-induced contractions of the rat uterus and gastrointestinal tract: ex vivo effect of long term streptozotocin-induced diabetes.

Rats were rendered diabetic by a single administration of streptozotocin (STZ). They were maintained in the diabetic state for six weeks before being killed, and diabetic state was confirmed by routine urine and blood glucose estimations. The contractile sensitivity of jejunum, colon, stomach fundus and uterus to carbachol was reduced in control animals by increasing buffer magnesium concentration from 1.9 mmol/litre to 23.8 mmol/litre. This magnesium effect was reversed in the colon, stomach fundus and uterus of streptozotocin-diabetic animals, with contractile sensitivity being enhanced in the presence of increased magnesium concentration. In the jejunum, however, the magnesium effect was not reversed by STZ-induced diabetes. In diabetic animals, magnesium generally had the opposite effect on gastrointestinal and uterine tissues when compared with control animals. This suggests that, in the diabetic condition, any altered gastrointestinal function may be due to an underlying difference in the sensitivity to changes in magnesium.

Animals↗

Aetiology of bacterial diarrhoea in north Indian children with special reference to Campylobacter jejuni.

A total of 184 cases of acute diarrhoea, in patients aged 1-36 months, were studied clinicobacteriologically. Enteropathogens were isolated in 22.28% cases. Campylobacter jejuni was isolated from 2.17% cases only. Salmonellae were isolated from 7.6% cases and 64.28% of them were S typhimurium. More than 75% of all isolates of salmonellae, shigellae, Esch coli and Campylobacter jejuni were sensitive to gentamicin and cephaloridine. Secondary lactose intolerance was noted in 6.52% cases only.

Campylobacter↗

Radiological score in the assessment of clubfoot.

The clinical appearance and the radiographs of 31 patients with 47 clubfeet taken before the start of treatment have been studied. In spite of making a careful clinical evaluation, 14 feet (29.8%) remained "borderline" and could not be definitely classified into the easy or resistant groups. The radiological score of the foot, which is an objective representation of the severity of the deformities at all important levels and in all planes, has been found to be an accurate and sensitive index which enables such a distinction to be made.

Ankle Joint↗