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Biomedical subjects

J Radcliffe

Publications and source records attributed to J Radcliffe.

41 records · Page 3Linked to original sources

A comparison of clonidine and standard provocative agents of growth hormone.

To evaluate the effectiveness of clonidine on growth-hormone (GH) release in prepubertal children, and to distinguish between a central alpha-adrenergic effect and a corticotropin-cortisol-mediated response, we measured serum glucose, corticotropin, cortisol, and GH concentrations following levodopa, arginine hydrochloride, and clonidine hydrochloride stimulation in 15 euthyroid children who had short stature. We found that clonidine is an effective and safe stimulator of GH release and provided a clearer distinction between GH-deficient and non-GH-deficient young persons than levodopa or arginine. The action of clonidine is not corticotropin-cortisol mediated.

Adolescent↗

The uniqueness of wave solutions for the deterministic non-reducible n-type epidemic.

In a recent paper, [8], we investigated the existence of wave solutions for a model of the deterministic non-reducible n-type epidemic. In this paper we first prove two properties left as an open question in that paper. The uniqueness of the wave solutions at all speeds for which a wave solution exists is then established. Only an exceptional case is not covered.

Disease Outbreaks↗

The spatial spread and final size of the deterministic non-reducible n-type epidemic.

A model has been formulated in [6] to describe the spatial spread of an epidemic involving n types of individual, and the possible wave solutions at different speeds were investigated. The final size and pandemic theorems are now established for such an epidemic. The results are relevant to the measles, host-vector, carrier-borne epidemics, rabies and diseases involving an intermediate host. Diseases in which some of the population is vaccinated, and models that divide the population into several strata are also covered.

Animals↗

Wave solutions for the deterministic non-reducible n-type epidemic.

A model is formulated to describe the spatial spread of an epidemic involving n types of individual. This encompasses the measles, host-vector and carrier-borne epidemics, and in addition rabies involving several species of animal. The existence, uniqueness and non-existence of wave solutions for different speeds are established for this model.

Animals↗