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Biomedical subjects

J R Varma

Publications and source records attributed to J R Varma.

9 recordsLinked to original sources
PubMed1992

Colon polyps.

Colonic polyps commonly occur in all age groups and are of varied significance depending on the type of polyp and the symptoms manifested. There is some debate in the medical literature regarding the appropriate clinical management of polyps and the follow-up of patients after polypectomy. This discussion addresses the significance of colon polyps, including their etiology, histology, complications, detection, and management.

Adenoma↗
PubMed1991

The practice outcomes of a course in flexible sigmoidoscopy for primary care physicians.

A mail survey of 430 participants in a 2-day course on flexible sigmoidoscopy presented over the past 6 years was conducted to determine the extent to which flexible sigmoidoscopy was subsequently utilized in physician practice. Eighty percent of respondents performed the procedure in their practices on a regular basis. Two-thirds of the patients underwent sigmoidoscopy for screening. The course in flexible sigmoidoscopy appears to potentiate the motivation of primary care physicians to incorporate complete colorectal cancer screening in their practice.

Education, Medical, Continuing↗
PubMedDate not supplied

Skin tags--a marker for colon polyps?

The frequency of colorectal cancer increased during the first half of the twentieth century, but for the last four decades, it appears to have stabilized. Today, the average American has a 5 percent probability of developing colorectal cancer during a 70-year life span. The majority of cases occur in persons aged greater than 50 years; the incidence increases up to age 75 years, after which there is a decline. Etiology is unknown; however, environment, genetics, and carcinogens have been implicated. Genetic relations of skin tags, colon polyps, and colon cancer are a matter of ongoing research. If such relations could be established, it could provide clinicians with a possible additional marker for persons at increased risk of colorectal adenoma and adenocarcinoma. Two cases are presented with a brief review of the literature.

Age Factors↗
PubMedDate not supplied

Colorectal cancer in patients aged less than 40 years.

Colorectal cancer is commonly found in adults aged greater than 50 years. The peak frequency occurs in the 6th to 7th decades and gradually declines in the 8th decade. This cancer is very unusual in young adults, the occurrence ranging from 1 to 17 percent of all cases of colon cancer. The prognosis for this disease in the young adult is reported to be unfavorable. This may be due to delayed diagnoses and a higher frequency of mucin-producing tumors and advanced stage of the disease. This article presents a case report and review of the literature and alerts the primary care physician to the possibility of serious disease in young adults who may present with protracted abdominal symptoms. Age should not be a barrier in the application of diagnostic tools. The duration and degree of symptoms should prompt early investigation.

Adolescent↗