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Biomedical subjects

J R Tagg

Publications and source records attributed to J R Tagg.

77 records · Page 5Linked to original sources

Pyocine typing as an epidemiological marker in Pseudomonas aeruginosa mastitis in cattle.

Pyocine typing was used for the characterization of 134 Pseudomonas aeruginosa strains isolated from bovine mastitis. The scheme of Gillies & Govan (1966) was adopted with some modifications, and the procedure gave 89.6% typability. Pyocine type 1 strains were most commonly encountered and were followed in frequency by types 10 and 3. The introduction of two additional indicator strains allowed for division of these types into subtypes.In spite of some limitations, discussed in the paper, the pyocine typing scheme proved to be useful in ;marking' P. aeruginosa strains and in following their association with bovine mastitis in various herds.

Animals↗

Diverse activity spectra of bacteriocin-like inhibitory substances having activity against mutans streptococci.

Mutans streptococci (MS) are known to be causative agents of dental caries. It has been suggested that these cariogenic bacteria could be eliminated from dental plaque by application of bacteriocins or bacteriocin-like inhibitory substances (BLIS). In the present study 272 bacterial strains of the genera Streptococcus, Enterococcus and Staphylococcus were tested for their production of BLIS activity against MS by use of a deferred antagonism test on agar media supplemented with either whole blood or yeast extract. Although only 14.3% of the test strains displayed anti-MS activity, the inhibitory agents produced by these strains were characterised by considerable diversity in the range of their inhibitory action against both MS and other common oral streptococcal species. It is suggested that combinations of relatively specifically targeted anti-MS BLIS may have potential application to the prevention of dental caries.

Antibiosis↗