Biomedical subjects
Publications and source records attributed to J R Sofat.
An unusual case of an extensive radicular cyst, involving almost the entire body of the mandible, is presented. A localised tooth trauma in the remote past appeared to be the initiating factor. The pathology of the lesion stem from necrotic apical periodontitis. Histopathology confirms the type of dental cyst.
Presented is an update on the current role of intra-arterial chemotherapy in the management of advanced maxillary sinus cancer. The potential benefit of such chemotherapy is that it permits the delivery of a high concentration of the cytotoxic agent directly to the tumour tissue bed in an effort to maximize the cytotoxicity and minimize the side effects. In such circumstances it is feasible to omit mutilating surgery and treat under an organ-sparing protocol without compromising survival.
From our study it is clear that lincomycin, given 300 mg intra muscularly daily in a single dose, is effective in a wide range of soft tissue infections especially those involving the head and neck region. An overall success rate of 88.8 per cent was observed in the 150 patients selected for the study. It is significant that in none of the subjects was any untoward reaction observed or reported. Hitherto all the previous systematic surveys on lincomycin appear to have been carried out on bone infections where, undoubtedly, lincomycin is highly effective. This pilot study furnishes an encouraging report on the successful treatment of soft tissue infections with parenteral lincomycin.
The clinical features, radiological findings, microscopic examination and treatment of a case of aneurysmal bone cyst have been discussed. The histopathological examination is the only way to confirm the diagnosis of this interesting bone lesion which rarely affects the jaws.
An interesting case of odontogenic keratocyst of the maxilla, with its clinical, radiological and histopathological findings, is reported. Total cystectomy resulted in a complete cure. Its histogenesis is discussed.
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