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Biomedical subjects

J R Ross

Publications and source records attributed to J R Ross.

At least 73 records · Page 4Linked to original sources
PubMed1980

Metabolism of arachidonic acid in inflamed human gingivae. I.: Formation of 6-keto-prostaglandin F1 alpha.

Incubation of [14C]-arachidonic acid with slices of inflamed human gingivae in the absence of glutathione resulted in formation of 6-keto-PGF1 alpha, the stable hydrolytic product of prostacyclin. Significantly smaller amounts of this product were obtained when normal gingivae were treated in a similar manner. The formation of prostacyclin in inflamed gingivae may play an important role in alveolar bone resorption and as a mediator of inflammation in periodontal disease.

Arachidonic Acids↗
PubMed1977

Unsuspected renal tumors associated with renal cysts.

A series of renal tumors associated with renal cysts is presented. Prior to surgical exploration appropriate diagnostic studies failed to indicate evidence of the presence of neoplastic lesions. The importance of surgical exploration of avascular "benign" renal masses is emphasized.

Adenocarcinoma↗
PubMed1977

Hematuria and sickle cell disorders.

To examine the relationship between gross hematuria and sickle cell disorders, all patients admitted to Grady Memorial Hospital with the diagnosis of a sickle cell disorder during a 14-month period were reviewed. Of 115 such patients, 65% had sickle cell disease and 35% had sickle cell trait. None of the former but seven of the latter group had gross hematuria. Mean age of the seven was 30 years. Comprehensive examinations and laboratory studies showed that all were free of concomitant disease. Physical findings, diagnostic modalities, and treatment were reviewed. Findings suggest that conservative therapy (bed rest, hydration, and diuresis) is usually effective.

Adolescent↗
PubMed1975

Observation of the mitochondria of the sulcular epithelium of clinically inflamed and clinically healthy gingiva.

Ten human males with an average age of 22 years, free from any known systemic disease, were selected for this study. Each subject had a mild gingivitis around at least one lower incisor tooth. This was confirmed by the color, contour, and consistency of the tissue. The area was probed for gingival sulcus depth and a radiograph confirmed that there was no interproximal bone involvement. A specimen was excised from the inflamed area and examined histologically for inflammatory cell density and an inflammatory index number was assigned to the tissue. The gingivitis was treated and personal oral hygiene instructions were explained to the subjects. Healing continued uneventfully for ten to twelve weeks. A second specimen was excised from near the original area, examined histologically, and an inflammatory index number was assigned to the tissue. The ultrastructure of the sulcular epithelium and the connective tissue adjacent to the sulcular epithelium of all specimens was examined at powers varying from 3,500 to 70,000. The sulcular epithelium showed no positively recognizable mitochondria. Mitochondria in the connective tissue adjacent to the basal layer of the sulcular epithelium were abundant and well formed. There was no correlation between the number and morphology of mitochondria in the treated and untreated specimens.

Adolescent↗