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Biomedical subjects

J R Nelson

Publications and source records attributed to J R Nelson.

92 records · Page 6Linked to original sources

[Cerebral computed x-ray tomography in acute lymphoblastic leukemia in children].

After analysis of the results of 142 CT brains scans performed from 1976 to 1982 on children with acute lymphoblastic leukemia, we can propose indications for this exam in relation with the different clinical stages and evolution of the disease. An exam is carried out as soon as possible at the start of the disease without injection of contrast media for use as a reference point. Excepting complications or neurological localisations, a scan will be performed at the end of the third year of treatment, without injection of contrast media, in screening for possible iatrogenic lesions. Neurological complications of unknown origin and leucoblastic meningitis seems to require a scan with injection of contrast media firstly as a mean of diagnosis, and secondly, in case of a cerebro meningeal localisation, in order to judge the efficiency of treatment and to screen for early complications. Computerized tomography however has its limits, particularly in case of purely meningeal leucoblastic infiltration.

Adolescent↗

Effects of the single-electrode cochlear implant on the vestibular system of the profoundly deaf adult.

Twenty-two profoundly deafened adults, implanted with the single-electrode cochlear implant, were involved in a study to observe the effects of cochlear electrical stimulation on the vestibular system. Previous investigators had found evidence that the implant might disrupt postural stability. As there had been no general complaints of dizziness or dysequilibrium by the implant subjects, a study was undertaken to replicate the earlier study and to compare the results to more standardized procedures. A Sono-postural Test was devised from the Ataxia Test Battery for the testing of balance with and without an auditory prosthesis. Electronystagmography was also performed on the subjects before and after surgery as a means of monitoring vestibular status over time. Results from the these tests indicate that the single-electrode implant does not disrupt the balance system to any significant degree. In fact, evidence indicates that postural stability may actually improve with the cochlear implant activated.

Adult↗