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Biomedical subjects

J R Masclans

Publications and source records attributed to J R Masclans.

20 records · Page 2Linked to original sources

[Energy requirement in patients after liver transplantation].

We have made a study of the energy requirements of liver transplant patients in the immediate post-operative phase, by comparing different methods. A study of energy use was made with indirect Calorimetry (IC), of calculation of Resting Energy Expenditure (REE) according to Fick's formula modified by Liggett, and of the calculation of basal energy Expenditure (BEE) applying Harris-Benedict's equation (HB). The correlation between the REE calculation using indirect calorimetry and that of BEE using Harris-Benedict (r = 0.7567) did not give a correction factor, applied to the Harris-Benedict formula) (REE by IC/BEE), which was uniform for all patients, oscillating as it did between 1.0 and 1.8. We found no correlation between REE by IC and that calculated using the modified Fick method, nor between the modified Fick method and BEE as calculated by Harris-Benedict. Our conclusion is that, with the IC method as reference to evaluate energy use, the Harris-Benedict calculation appears to be more reliable than that using the modified Fick equation and that, in the group of patients studied, and given the individual variations in the REE ratio calculated by IC and the BEE calculated by HB, we were unable to find a suitable correction factor for them all. IC is therefore the ideal method for evaluating energy use in critical patients in the ICU.

Basal Metabolism↗

[Lipid emulsions and pulmonary function].

A review is made of possible adverse effects of lipid emulsions on the respiratory function, based on the use and acceptance thereof as part of the non-protein caloric supply of the total parenteral nutrition of critical patients from the first hypotheses of the role played by the subsequent lipemia, to the most recent which lend great importance to the eicosanoids generated by the fatty acids supplied by the lipid emulsions. It is also verified whether the observed effects are similar both in healthy as well as in damaged lungs. Another variable to keep in mind, is the rate of administration of the lipid emulsions, which, related to the clearance thereof, could have different actions. Finally, and due to the fatty acid pattern of the lipid emulsion being different than that of the chylomicron, it is evaluated whether the actions of these emulsions may vary as a function of the quantity and quality of the fatty acids supplied.

Animals↗