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Biomedical subjects

J R Kamat

Publications and source records attributed to J R Kamat.

36 records · Page 2Linked to original sources
PubMed1992

AIDS with special reference to pediatric aspect.

The article discusses the disease AIDS, and its increasing incidence all over the world. The alarming rise of HIV infection amongst those tested in India is noted. The projection as made by WHO are mentioned. The various modes of transmission of HIV infection and the high risk groups for each mode are identified. Clinical manifestation of an adult case is followed by that of a pediatric patient in whom the infection is mostly transplacental. The risk of TAA amongst children is highlighted as also the difference between adult and pediatric AIDS. Diagnosis of AIDS, its management, prognosis and prevention are mentioned. The similarity between HIV-1, SIV and HIV-2 induced immunodeficiency is recorded.

Acquired Immunodeficiency Syndrome↗
PubMed1987

Polymorphonuclear leukocyte functions in patients with acute rheumatic fever and rheumatic heart disease.

Polymorphonuclear (PMN) cell function was assessed in 30 children with active rheumatic fever (ARF) (Group I), 30 cases with active rheumatic heart disease (RHD) (Group II), 28 cases of ARF and RHD in remission (Group III) and 34 adults with quiescent RHD along with their age matched controls. All the groups showed normal spontaneous and chemotactic movement. Phagocytosis of yeast particles was significantly reduced in groups II (P less than 0.0005), III (P less than 0.025) and IV (P less than 0.005). The opsonic activity of disease sera was low in all 4 groups (P less than 0.0005). The intracellular metabolic activity was moderately elevated in Group III. Phagocytosis and opsonic activity were thus persistently low in all the groups including the remission and quiescent group.

Adolescent↗
PubMedDate not supplied

Congenital nephrotic syndrome with clinical hypothyroidism.

A 15 month old boy with typical features of congenital nephrotic syndrome (CNS) is reported, who in addition to the renal pathology had an associated clinical hypothyroidism with low levels of total and free thyroxine and triiodothyronine and an elevated serum TSH. Improvement in the physical parameters and mental status from thyroid hormone replacement therapy is documented.

Enalapril↗
PubMedDate not supplied

Effect of passively transferred anti-poliovirus antibodies on seroconversion.

A prospective study enrolling 50 mother-infant pairs was undertaken to determine the effect of maternal antibodies on poliovirus antibody titres and seroconversion rates in infants and to determine the difference in titres and seroconversion rates following three and five doses of oral poliovaccine (OPV). Cord blood samples and samples collected 4 weeks after 3rd and 5th doses of trivalent oral poliovaccine were processed for estimation of anti-poliovirus antibody titres. These were expressed as geometric mean titres (GMT). Significance was analyzed using unpaired 't' test. The relationship between maternal antibody titres and seroconversion was determined by correlation coefficient test. Post OPV5 titres were significantly higher than post OPV3 titres for type 1 and type 2 polioviruses. Seroconversion rates against type 1, 2 and 3 polioviruses were 92.9%, 100.0% and 92.9% following OPV3 and 100.0%, 100.0% and 93.2% following OPV5. The cord blood titres did not have any relation to post-OPV3 or post-OPV5 titres. Although there is significant passive transfer of poliovirus antibodies across the placenta, this does not affect titres achieved after immunization. Post-OPV5 titres against type 1 and type 2 viruses are significantly higher than post-OPV3 titres. The seroconversion rates following OPV5 are higher than those obtained post-OPV3 but this difference is not statistically significant.

Adult↗
PubMedDate not supplied

Intramedullary spinal cord abscess.

Intramedullary spinal cord abscess is a treatable cause of paraparesis. Magnetic resonance imaging is an important diagnostic modality. Combination of antimicrobial therapy and surgical intervention can provide good results in patients with subacute presentation.

Abscess↗
PubMedDate not supplied

Chloroquine induced parkinsonism.

A case of parkinsonism is reported in a 5-years-old male child following prolonged use of chloroquine. The patient presented with reduced spontaneous movements and speech with an expressionless face and a parkinsonian gait but no tremors. His investigations including CT scan brain, CSF study and serum ceruloplasmin were normal. Chloroquine was discontinued and the patient was started on oral trihexyphenidyl. The patient showed gradual recovery and the drug was successfully withdrawn. The toxic manifestations were only transient and reversible.

Antimalarials↗
PubMedDate not supplied

Paediatrics in India.

Explore the source record for details and available documents.

History, 20th Century↗
PubMedDate not supplied

Imprint cytology in the diagnosis of breast tumor.

Fifty breast lumps seen and operated on at the Goa Medical College Hospital over a one year period form the material for this study. The cases were at first diagnosed clinically. At operation a naked eye assessment of the malignancy of the excised breast lump was made. Slide imprints for cytodiagnosis were made and finally the excised mass sent for paraffin section study. A rapid diagnosis of these 50 surgically removed breast lumps was thus made by naked eye examination and imprint cytodiagnosis and the results were compared with routine paraffin section diagnosis which is considered the final diagnosis. An analysis of the results show that naked eye examination of the excised breast lump distinguished between malignant and non-malignant lumps correctly in 96% of cases, rapid imprint cytodiagnosis was correct in 98% of cases, clinical diagnosis in 96% of cases and aspiration cytodiagnosis in all cases. Naked eye examination of the mass prior to imprinting would help to decide the correct pressure to be used to avoid false results.

Breast Neoplasms↗
PubMedDate not supplied

Massive haemoptysis controlled by bronchial artery embolisation: a case report.

Massive haemoptysis results in a high rate of mortality and morbidity. It is infrequently seen in children. Medical and surgical interventions are not very effective in controlling torrential bleeding. Therefore, newer modalities like bronchial artery embolisation are found to be promising in life threatening situations in both adults and children.

Bronchial Arteries↗