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Biomedical subjects

J R Jasmin

Publications and source records attributed to J R Jasmin.

At least 37 records · Page 2Linked to original sources

[The oro-dental status of a population of school children in the southeast of France].

This cross-sectional investigation, part of a national epidemiological survey, studied the oral conditions of schoolchildren, aged 6 to 15 years, of the South East of France. This region is mainly urban and the drinking water has a low fluoride content. The highest dft and dfs indices were observed respectively at 6 and 8 years from when they decreased. The DMFT and DMFS indices increased progressively from 6 years on. This study confirmed a North-South difference in caries prevalence since the observed values of the caries indices were similar to those of other mediterranean countries like Greece and Italy. The observed caries indices were higher than the mean indices of France and the rest of Europe. This South East region of France therefore needs special care from the dental profession and the french authorities.

Adolescent↗

S-100 immunolabelling of Langerhans cells in oral epithelium.

Langerhans cells (LCs) are dendritic cells usually present in the suprabasal regions of squamous epithelia remarkable by the presence of Fc IgG and C3 receptors, Ia/Dr, T-6 and T-4 antigens on their membranes. Conventional and immunohistochemical techniques for identification of LCs require special fixation procedures and are incompatible with paraffin embedding. A method for staining LCs, in routine fixed and paraffin-embedded material, based on the use of antiserum against S-100 proteins is presented. The problem arising from the simultaneous staining of melanocytes is discussed. S-100 positive dendritic cells should be considered as LCs when fulfilling 3 criteria: located in the suprabasal layers of the epithelium; the whole cell body being visible; with at least one dendritic process.

Dendritic Cells↗

Dentinogenesis imperfecta type III with enamel and cementum defects.

Ground sections and scanning electron microscopic studies of primary teeth from a 2-year-old child whose teeth showed absence of enamel and large pulp chambers are examined. The findings suggest a diagnosis of odontodysplasia in a case classified as dentinogenesis imperfecta type III.

Child, Preschool↗

A scanning electron microscopic study of dentin dysplasia type II in primary dentition.

Dentin dysplasia type II is a rare autosomal dominant defect which affects dentin formation in both the deciduous and the permanent dentitions. The scanning electron microscopic study performed on a primary central incisor presents some findings similar to those reported in dentinogenesis imperfecta. Because of the lack of published reports on dentin dysplasia type II, it is difficult to ascertain definitive characteristics of this dentin abnormality.

Child, Preschool↗

Studies of bone and soft-tissue tumours induced in rats with radioactive cerium chloride.

A colloidal suspension of radioactive cerium chloride was inoculated into the hind legs of Sprague Dawley rats. Bone and soft-tissue tumours were induced at the site of inoculation in 77% of the animals. All bone tumours were osteogenic osteosarcomas. Soft tissue tumours were mostly malignant and were of various histological types, predominantly fibrosarcomas, haemangiopericytomas, angiosarcomas and rhabdomyosarcomas. A kinetic study showed that the doubling time (DT) of tumours was closely correlated with the anatomical site of tumour development: bone tumours had a DT of 17.4 +/- 4.3 days and malignant tumours which developed in soft tissues had a DT ranging from 7.4 to 8.4 days with the exception of two haemangiosarcomas which had a long DT of 17 +/- 0.6 days. Pulmonary metastases were frequent for osteosarcomas and tumours of vascular origin. This model of induction of bone and soft-tissue tumours in rats by injection of a colloidal suspension of radioactive cerium chloride offers the possibility of more comprehensive physiopathological and kinetic studies of these tumours and may constitute a good model for their human counterparts.

Animals↗

Induction in rats of paranasal sinus carcinomas with radioactive cerium chloride.

A colloidal suspension of radioactive cerium stabilized in the form of hydroxide was inoculated into young Sprague-Dawley rats near the maxillary sinus. Well-differentiated epidermoid carcinomas of the paranasal sinus were obtained in 8 of 12 rats and in 8 of 9 animals that liver more then 200 days. Therefore, this istope was highly effectivein inducing tumors at the site of injection. The uniformity of the histologic type of tumors induced under these experimental conditions was remarkable.

Animals↗