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Biomedical subjects

J R Goldsmith

Publications and source records attributed to J R Goldsmith.

At least 127 records · Page 7Linked to original sources
PubMed1970

Epidemiology of chronic bronchitis in Prague.

A number of epidemiological studies in several countries have implicated cigarette smoking, occupation, age, sex and air pollution as well as other environmental factors in the epidemiology of chronic respiratory disease. This paper reports the results of a respiratory-symptom and pulmonary-function survey among a large population of men aged 50-65 years in Prague. In general, the findings of other studies have been confirmed, showing that these relationships occur in an even wider range of geographic and cultural backgrounds. In addition, the study uncovered an apparent relationship between the occurrence of respiratory symptoms and a family history of chronic bronchitis and tuberculosis, suggesting that future surveys should include studies of familial aggregations of chronic respiratory disease. Similar studies have been carried out in other parts of Czechoslovakia with different levels of air pollution for comparison with the results of this study.

Aged↗
PubMed1970

The new airborne disease. Community air pollution.

Community air pollution is the new airborne disease of our generation's communities. It is caused by the increasing use of fuel, associated with both affluence and careless waste. Photochemical air pollution of the California type involves newly defined atmospheric reactions, is due mostly to motor vehicle exhaust, is oxidizing, and produces ozone, plant damage, impairment of visibility and eye and respiratory symptoms. Aggravation of asthma, impairment of lung function among persons with chronic respiratory disease and a possible causal role, along with cigarette smoking in emphysema and chronic bronchitis, are some of the effects of photochemical pollution. More subtle effects of pollution include impairment of oxygen transport by the blood due to carbon monoxide and interference with porphyrin metabolism due to lead. Carbon monoxide exposures may affect survival of patients who are in hospitals because of myocardial infarction. While many uncertainties in pollution-health reactions need to be resolved, a large number of people in California have health impairment due to airborne disease of this new type.

Air Pollution↗
PubMed1967

Respiratory exposure to lead: epidemiological and experimental dose-response relationships.

Epidemiologic studies of blood lead levels in general and occupational groups show a logarithmic regression on estimated atmospheric exposure. Experimental results at the same and higher levels show a dose-response relationship which fits the same regression. The data imply that long-term increases in atmospheric lead will result in predictably higher blood lead levels in the exposed populations.

Adenosine Triphosphatases↗