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Biomedical subjects

J R Gallagher

Publications and source records attributed to J R Gallagher.

13 recordsLinked to original sources

The nutritional status of pregnant and non-pregnant mares grazing South East Queensland pastures.

It has been reported that the increasing nutritional demands from mid to late pregnancy of grazing mares may not be met when these stages of gestation coincide with pastures being affected by frost. It was established in this study that grass/legume pastures could support the nutritional requirements of brood mares by providing digestible energy intakes of 68.0 and 91.7 MJ/day and digestible nitrogen intake of 91.2 and 138 g/day during mid and late pregnancy, respectively.

Animal Feed

Inhibition of brain monoamine oxidase by 1,2,4-trisubstituted 5-imidazolones.

Nine 1-(3,4-dimethoxyphenethyl)-2-methyl-4-(substituted benzylidene)-5- imidazolones were evaluated for their ability to inhibit the activity of rat brain monoamine oxidase during oxidative deamination of tyramine, 5-hydroxytryptamine (serotonin), and kynuramine. All substituted imidazolones inhibited monoamine oxidase activity. A concentration-dependent inhibition of monoamine oxidase was observed using kynuramine as the substrate and the degree of enzyme inhibition was also evaluated on the basis of their I50 values. Preincubation of imidazolones with the enzyme preparations for varying lengths of time prior to the addition of substrate in no way altered their degree of inhibition and thus exhibited a reversible nature of inhibition. A kinetic study carried out with 1-(3,4-dimethoxy-phenethyl)-2-methyl-4-(4- nitrobenzylidene )-5- i midazolone revealed a competitive nature of inhibition of rat brain monoamine oxidase.

Animals

The origins, development, and goals of adolescent medicine.

This essay offers the author's recollections and opinions on such topics as when and why an interest in adolescents' medical care originated, under what circumstances those developments occurred which preceded and soon followed the recognition of Adolescent Medicine by medical schools and hospitals, and the goals of those physicians who pursued that interest. It attempts to recount and document the events, circumstances, persons, and groups of people associated with the emergence and early development of this venture into the medical care of yet another age-group.

Adolescent

Child development.

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History, 20th Century