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J R Domínguez

Publications and source records attributed to J R Domínguez.

16 recordsLinked to original sources

Degradation of olive mill wastewater by the combination of Fenton's reagent and ozonation processes with an aerobic biological treatment.

Degradation of olive mill wastewater (OMW) by means of two chemical oxidation processes (Fenton's reagent and ozonation) and their consecutive treatments with aerobic microorganisms have been studied. Fenton's reagent treatment moderately reduces COD and to a greater extent the polyphenolic compounds. Ozonation contributed to low conversion of COD and moderate reduction of polyphenols. The aerobic biological treatments degrade to values higher than 70% and 90% for COD and polyphenolic compounds, respectively. A kinetic study has been carried out in each process, determining the representative kinetic parameters of each model.

Bacteria, Aerobic↗

[Heart disease in acromegaly. Study of 27 patients].

BACKGROUND: The patients with acromegaly have an increased propensity to develop cardiovascular complications. The aim of this study was to evaluate the most relevant clinic, echocardiographic and Holter recording findings in acromegaly and its correlation with the growth hormone (GH) levels and duration of the disease. PATIENTS AND METHODS: 27 patients with acromegaly were evaluated. The basal levels of GH and insulin-like growth factor 1 (IGF-1) were measured at the time of cardiological study and compared with the spontaneous GH secretion during 12-24 hours previously studied. Echocardiogram was made using complete M-mode, two dimensional and spectral Doppler ultrasound mechanical system. Additionally an standard EKG and a Holter recording were performed during 24 hours. RESULTS: There was a strong correlation between basal levels of GH and integrated concentration of GH during the study of spontaneous secretion (r = 0.92; p < 0.01). The prevalence of symptomatic cardiovascular complications in this study was 49%, including 3 patients who died for cardiovascular events. The echocardiographic study showed a high prevalence of left ventricular hypertrophy (66.7%), diastolic dysfunction (63%) and impaired systolic function (18.5%). There was no correlation between GH and IGF-1 levels and echocardiographic findings. Conversely the degree of hypertrophy was related to the duration of the disease and the presence of arterial hypertension. The diastolic function only was related with the presence of hypertension. We found supraventricular arrhythmic events and malignant premature ventricular complexes in 6 and 6 patients, respectively. The EKG showed a high fiability to detect ventricular hypertrophy but no rhythm events. CONCLUSIONS: The high prevalence of cardiovascular complications in acromegaly, most of them asymptomatic, and its clinical relevance, advise the necessity to perform systematic cardiovascular evaluation in these patients.

Acromegaly↗

[Pharyngeal carriers of Neisseria meningitidis and N. lactamica in childhood].

A prospective study was undertaken with the purpose of finding out the proportion of pharyngeal carriers of N. meningitidis and N. lactamica among our infantile school population. Seven groups constituted by, approximately, 200 infants each, were studied along two years. Samples were taken in two different schools, for each each group, at a period of average incidence (February, April, June and October). Infants were between five and six years of age and made a total of 1,315 individuals, which we consider representative of our school infantile population. Positivity for N. lactamica was around 20%, whereas 10% of infants were carriers of N. meningitidis. Among the latter 56% were group B, 15% group Y, 5% group A and 20% agglutinated spontaneously. The remainder fell into several serogroups (10 unclassifiable, six 29E and one each, X, W135 and Z). Concerning group B serotypes, except for 22 not typable cases, most carriers were serotype 2, while the remainder were distributed in seven other serotypes. These findings are comparable to those seen in the population with clinical disease. However the number of carriers remained constant and, in contrast to what happened with clinical patients, was unrelated to seasonal variations. Resistance of N. meningitidis to chemotherapy was the following: sulfadiazine 100%, ampicillin 19%, rifampicin 20% and penicillin 0%. The latter can not be considered a good choice in prophylaxis.

Anti-Bacterial Agents↗

Accuracy of combined clinical findings and fine needle aspiration cytology for the diagnosis in palpable breast tumors.

OBJECTIVE: A prospective study to evaluate the confidence level and predictive value of the fine needle aspiration biopsy was performed in the Oncology Service, "Hospital 20 de Noviembre, ISSSTE", Mexico City. MATERIAL AND METHODS: The cases with a palpable breast tumor, histologically confirmed who presented from 1992 to 1994 were included. One aspirate was done in each patient and these were reviewed by the same pathologist. We determined sensitivity, specificity and predictive value of the test. Age, border characteristics, size and mobility of the tumor were evaluated by Bayesian analysis. RESULTS: From 213 aspirates, 199 were elegible for diagnosis, 98 (46%) had a diagnosis of carcinoma, 13 were acellular and one suggestive. The acellular diagnoses were considered negative and suggestive positive, for analysis purposes. Mean age and tumor size were: 46.6 years (range 14-90) and 3.7 cm. (range 1-13) respectively. Sensitivity (0.932), specificity (0.973) and positive predictive value (96.9%) were estimated. We observed a high probability of true positive [P(D+/T+)] > 0.8 results in patients between 40 and 60 years of age, irregular borders, size > 2 cm and fixed lesions. CONCLUSIONS: The test has a high confidence level and in presence of two or more of the clinical factors mentioned, definitive decisions regarding treatment could be taken, without need of histologic confirmation.

Adolescent↗

[Pancreatic insufficiency: an infrequent manifestation of primary hyperparathyroidism].

A case of malabsorption of pancreatic etiology secondary to primary hyperparathyroidism (HPT) is reported. Normalization of calcemia was achieved with parathyroidectomy and oral administration of pancreatic enzymes was initiated. HPT is an infrequent cause of pancreatic inflammatory disease. Although its association is controversial, its inclusion among the causes of exocrine pancreatic failure allows correct diagnosis and therapeutic management with a favorable prognosis.

Combined Modality Therapy↗