Search PubMed⌕ Search

Biomedical subjects

J R Collin

Publications and source records attributed to J R Collin.

84 records · Page 5Linked to original sources
PubMed1979

Terminal course of nerve supply to Müller's muscle in the rhesus monkey and its clinical significance.

Electron microscopic, histochemical fluorescence, and pharmacologic evidence suggested that, in the rhesus monkey, Müller's muscle was not totally denervated either by cutting the levator palpebrae superioris muscle or by a Fasanella-Servat procedure. We examined the terminal course of the sympathetic nerve supply and the potential for preserving Müller's muscle in blepharoptosis surgery.

Adrenergic Fibers↗
PubMed1979

Blepharochalasis.

The condition of blepharochalasis and its treatment are discussed. Four cases are presented which show a physical sign that may help in its diagnosis.

Adolescent↗
PubMed1979

A ptosis repair of aponeurotic defects by the posterior approach.

A simple posterior approach operation for correcting ptosis due to a disinsertion of the aponeurosis of the levator palpebrae superioris muscle is presented. Müller's muscle is restored to its normal length. Pull-out sutures are used which give some postoperative control of eyelid level and allow the procedure to be done under general anaesthesia if required.

Blepharoptosis↗
PubMed1979

Cyclic oculomotor palsy.

This rare condition, an oculomotor palsy which is interrupted by spastic contractions of the levator muscle and the pupillary sphincter at fairly regular intervals, had been reported in 54 patients up to 1975. Two patients presented to the authors with apparently complete unilateral ptosis but abnormal pupillary reactions prompted closer examination. Once the diagnosis has been considered only 5 minutes of careful clinical examination are necessary to confirm or reject it. During the past 4 years the authors have found nine new cases of the condition and it is clear that the diagnosis must often be missed. Details of the patients are shown and discussed in the light of Loewenfeld and Thompson's theory of the pathology. The place of surgical treatment is considered.

Adult↗
PubMed1978

Involutional entropion. A review with evaluation of a procedure.

The pathophysiologic changes that lead to involutional entropion are discussed. The Quickert entropion operation gives good results because it rectifies the effect of enophthalmos; it restricts the upward movement of the preseptal muscle; it repairs the relaxation or disinsertion of the lower eyelid retractors; and it corrects the buckling of the upper tarsal border. Using this procedure, the recurrence rate of 3.7% is comparable with that of other procedures.

Adolescent↗
PubMed1978

Experimental and clinical data on the insertion of the levator palpebrae superioris muscle.

Radiographic and electron microscopic evidence showed that the upper eyelid skin crease is formed by the insertion of the levator palpebrae superioris muscle into the septa between the orbicularis muscle into the septa between the orbicularis muscle bundles and not into the skin itself. Experiments on monkeys showed that the insertions of the aponeurosis and of Müller's muscle both contribute to normal eyelid elevation. No histologic evidence was found for a disinsertion of Müller's muscle in 20 cases of blepharoptosis. This, with other evidence discussed, supports the functional importance of the human aponeurotic insertions in eyelid elevation.

Adolescent↗
PubMed1978

Cryosurgery for trichiasis.

A series of 41 cases of trichiasis was treated with cryosurgery using a standard retinal cryoprobe. The failure rate was approximately 50 per cent. The results should be improved by using properly designed equipment capable of cooling the lash follicles to -20 degrees C, and ensuring that this temperature is achieved by using a tissue thermocouple. A double freeze-thaw cycle should be used and a long-acting local anaesthetic containing adrenaline. The main complication is depigmentation which is a problem only with heavily pigmented patients. Cryosurgery does have potential for the treatment of trichiasis.

Adolescent↗
PubMed1975

Peritoneal autografts in conjunctival replacement.

Twenty-eight rabbits underwent conjunctival replacement with peritoneal autografts. The grafted peritoneum acted as a scaffold for the remaining healthy conjunctiva which gradually replaced the grafted peritoneum. Peritoneum is not an effective conjunctival substitute as it does not survive in its own right. I should like to thank Professor Norman Ashton, FRS for his most helpful guidance and constructive criticism in this work. My thanks are also due to Miss E. Robins for her enthusiastic technical support; to Mr. R. Alexander and Mr R. Keeble for their technical and photographic assistance, and to Miss E. FitzGerald for her secretarial help.

Animals↗