Automated analysis of ultra high-speed laryngeal films.
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Computers↗
Biomedical subjects
J R Booth
Publications and source records attributed to J R Booth.
A rapid automated latex screen for tetanus toxoid antibodies.
This report describes the sensitisation of latex particles and the use of this reagent on the Autotape system to select blood donations containing greater than or equal to 4 IU/ml of tetanus toxoid antibody. Plasma containing tetanus toxoid antibodies is processed to provide immunoglobulin for passive protection against tetanus. The techniques used for screening include immunoelectrophoresis [3], tetanus toxoid sensitised latex particles [5], haemagglutination [1] and automated haemagglutination [6]. The technique used by the Sheffield Regional Transfusion Centre until recently, was immunoelectrophoresis, selecting donors with 4 or more IU/ml. The Autotape system, previously described for brucellosis [4] and syphilis testing [2], provides a system for automated slide testing and a 5-min tetanus toxoid coated latex test has been developed to select suitable donations for the production of specific immunoglobulin.
Agglutination↗
Automation of the rapid plasma reagin test using the Autotape System.
The paper describes the Autotape System, a new piece of apparatus which is automated slide testing equipment, and its successful application to the rapid plasma reagin test.
Antibodies↗
Separation of hepatitis-associated antigen (HAA) from human plasma for the production of rabbit anti-HAA.
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Ammonium Sulfate↗
The effect of heat on the A, B, and H antigenic strength of human red cells.
The reaction of A cells with anti-A, B cells with anti-B, O cells with Ulex europaeus anti-H is reduced by heat (56 degrees C) treatment. This is demonstrated using an automated haemagglutination technique with which minor differences in reactions can be detected.
ABO Blood-Group System↗
Large-scale screening by the automated Wassermann reaction.
In view of the drawbacks in the use of the Kahn test for large-scale screening of blood donors, mainly those of human error through work overload and fatiguability, an attempt was made to adapt an existing automated complement-fixation technique for this purpose. This paper reports the successful results of that adaptation.
Automation↗
Developmental differences in visual and auditory processing of complex sentences.
Children aged 8 through 11 (N = 250) were given a word-by-word sentence task in both the visual and auditory modes. The sentences included an object relative clause, a subject relative clause, or a conjoined verb phrase. Each sentence was followed by a true-false question, testing the subject of either the first or second verb. Participants were also given two memory span measures: digit span and reading span. High digit span children slowed down more at the transition from the main to the relative clause than did the low digit span children. The findings suggest the presence of a U-shaped learning pattern for on-line processing of restrictive relative clauses. Off-line accuracy scores showed different patterns for good comprehenders and poor comprehenders. Poor comprehenders answered the second verb questions at levels that were consistently below chance. Their answers were based on an incorrect local attachment strategy that treated the second noun as the subject of the second verb. For example, they often answered yes to the question "The girl chases the policeman" after the object relative sentence "The boy that the girl sees chases the policeman." Interestingly, low memory span poor comprehenders used the local attachment strategy less consistently than high memory span poor comprehenders, and all poor comprehenders used this strategy less consistently for harder than for easier sentences.
Age Factors↗