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Biomedical subjects

J R Ahued Ahued

Publications and source records attributed to J R Ahued Ahued.

At least 19 recordsLinked to original sources

[Dilated myocardiopathy and pregnancy. Report of 3 cases and review of the literature].

Pregnancy in association with dilated cardimyopathy is considered to be a rare entity. The incidence is unknown. The dilated cardiomyopathies (DCM) are defined as diseases of the cardiac muscle without a known cause. Three pregnancies with DCM are reported. In this article the possible hazzards of pregnancy and DCM are discussed, including a review of the literature concerning to diagnosis and management is present.

Adolescent↗

[Initial experience with a minidose of methotrexate in the management of unruptured ectopic pregnancy].

Methotrexate has been used in the conservative management of ectopic pregnancy with good results. Due to its great afinity for the trophoblast it was decided to try unique doses of 50 mg i.m. independently of the body surface. Fifteen patients were studied with ectopic pregnancy by ultrasound and hCG in series that didn't require confirmatory laparoscopy. The ectopic pregnancies broken and/or decompensated were discarded. Average gestational age was 6.1 weeks; the maximal dimention of the sacs was 36.8 mm average; the values for hCG average were 6440 mU/ml and the maximal time of negativization was 52 days. One patient required laparoscopy and salpingostomy, lineal, for inminent rupture 24 hour after methotrexate, the other 14 presented with complete remission. There were no colateral effects. From the 15 patients, in 6 tubal permeability was confirmed by laparoscopy or HSG, being positive in 6 patients, it has not been evaluated, two patients with resolved pregnancy, and other on course (two of them with one salpinx). The proposed management seems to be useful in ectopic pregnancy with success, equivalent to surgical management, and other programs of medical management, with out side effects and with greater easiness of administration.

Chorionic Gonadotropin↗

[AIDS and pregnancy].

Near 70 per cent of Mexican women infected by the Human Immunodeficiency virus (HIV) are between 15 and 44 years old, in this women sexual transmission are the most frequent route of infection. The objective of this article was to describe the obstetric course and perinatal repercussion of the HIV-Positive pregnant women with medical care at the Instituto Nacional de Perinatología, Mexico city between January 1994 to December 1996. Nineteen women were studied, sexual transmission was the route of infection in 16 of them. One had diagnostic criteria for AIDS, the others 18 had HIV asymptomatic infection. At delivery 18 a term products were born. The mean of the newborn weight was 3159 g. At moment of this report 4 children (22%) have been diagnosed as HIV infected, all of them dead during their first year of life.

Acquired Immunodeficiency Syndrome↗

[Cesarean section: science or anxiety? Eleven years of institutional experience].

The increasing rise of cesarean section rate invites to analyze its indications. The present study was done from 1985 to 1995, which means 11 years of study with 38,407 cases. Frequency and clinical indications were analyzed. As to births, frequency was 40.6%. Main causes were: Iterative section 38.2%; cephalopelvic disproportion 28.1%; pelvic presentation, 23.4%; hypertensive disease in pregnancy 16.3%; and acute fetal suffering, 10.9%. The careful observation of indications in every institution, may produce better reasons for reducing such high indexes.

Analysis of Variance↗

[Scuba diving and pregnancy. A case report and review of the literature].

The number of women in childbearing age participating in SCUBA dividing is increasing. Some dives during first trimester before pregnancy is confirmed. The preoccupation of both parents, is that the child could have any damage in the embryonal stage. This is a review of the literature and we present one case of a patient 28 years old with one immersion of 25 meters, at 28 days of gestation. The child did not present any congenital deformity at birth and his growth and development in the eighteen months have been normal.

Adult↗

[Ultrasonic measurement of the cerebellum in the newborn infant as a prognostic index of gestational age. (A preliminary study)].

This paper studies if cerebellum measurement by ultrasound is a point of prognostic value for evaluation of gestational age. Ninety-nine neonates of different age of gestation, were studied. Ultrasonographic study of the cerebellum was done in all the cases during the first 24 hours of life. It is suggested that the cerebellum measurement may be one indicator more for the evaluation of gestational age, and therefore of value to identify the products with growth disturbances.

Analysis of Variance↗

[The use of prostaglandins for labor conduction in its latent phase].

We wanted to know enprostil efficacy, an E2 prostaglandin analogous as a labor conductor in it's latent phase in term pregnancies. 188 patients were included, 52% received intracervical enprostil and 48% were treated with oxytocin. The labor evolution, resolution and complications were watch over. 15 patients (15.6%) of the study group required labor conduction with oxytocin because it was inhibited after peridural anesthesia. The main pregnancy resolution was vaginal via; only 6.3% of the study group subjected cesarean section against 10.3% of the witness group and the most frecuent indication was stationary dilation (1 and 8 cases respectively). The time of the latent phase and total labor was lower statistically in the study group. The observed complications were post-labor hemorrhage (3.1%), polysystolia (4.1%) and vomiting (5.2%), without significant difference with the witness group. We conclude that intracervical enprostil help cervical mature. shortenning latent phase and total labor, disminish oxytocin requeriment and cesarean incidence by cervical alterations without compromise maternal-fetal morbi-mortality.

Enprostil↗

[Proposed normal values for alpha fetoprotein in maternal serum for the detection of neural tube closure defects and Down syndrome. Preliminary study].

To establish a normal range of alpha fetoprotein in maternal serum (AFP sm) in the population at the "20 de Noviembre" Hospital in Mexico City, there were studied 46 patients with a normal pregnancy confirmed with ultrasonography between 16 to 18 week of gestation. The 97 determinations of AFPsm were made by radioimmunoanalysis. The multiples of the median (MoM) were 2.16 al 16th weeks, 2.33 a 17th week 2.43 al 18th week of pregnancy. Now the methods to determine abnormalities in the product and the genetics studies are proposed only to the patients considered high risk (older than 35 years old, previous malformed son or family history of those abnormalities). AFPsm and the establishment of normal range allow us to amplify the study to every pregnant woman and to determine those malformations in the pregnant women of low risk which represents about 90-95% of DCTN and about 80% of SD.

Adult↗

[Usefulness of the flame test in the diagnosis of premature rupture of fetal membranes].

A prospective, experimental and comparative study, was carried out at the Labor Service and Perinatology Service at Gyn-Ob Division, Regional Hospital "20 de Novembre" ISSSTE, Mexico City, during the period from September 1st, 1987 to September 1st., 1988. The objective was to demonstrate usefulness of the Flame Test in the diagnosis of premature rupture of membranes (PRM). A total of 116 samples from patients randomly selected, in four groups (3 controls and one problem group), were studied. The test was used in comparison with crystallography. Age, gesta, parity, abortion and cesarean section, and birth's via, as well as the antecedent of use of anticonceptives, were studied. Twenty six samples in Group I, 10 in Group II, 40 in Group III and 40 in Group IV, were obtained. The statistical method of X,2 was used, and a statistically significant difference (p.05), was obtained, with a sensitivity of 97.8%, and specificity of 100%, a predictive value of 100%, and security of 98% for the test. It's concluded that the Flame test is useful in the diagnosis of PRM, with a low cost, a high sensitivity, and a similar specificity to the reported one by others.

Adolescent↗

[Alternative management of iron deficiency anemia in pregnancy and puerperium].

An open, observative, prospective, follow-up study was performed in 80 obstetric patients at the 20 de novembre Hospital in Mexico city between november 1986 and august 1987. There were two groups: 40 pregnant patients (between 15 and 35 weeks of pregnancy), and 40 puerperants (between 1st and 6th day or puerperium), both groups had confirmed diagnosis of iron deficiency anaemia; iron-deficiency was estimated upon haemoglobin level, patients body weight and obstetric status. After that, diluted dextran-iron was infused intraveously, six weeks after iron infusion the patients were evaluated. Haemoglobin, haematocrit and red blood cell levels showed a significant rise. Abnormalities observed in the blood smear decreased; 10% of the patients in both groups showed slight secondary reactions, which were self-limited or subside with medical therapy.

Adolescent↗

[Genetic amniocentesis].

179 patients were studied by genetic amniocentesis (GA) in sessions of 3 punctures each. This was done in order to follow a prenatal diagnosis (PD) program and study amniotic fluid at the Hospital Regional 20 de Novembre (ISSSTE) between May 1983 and December 1987. The parameters taken were: age, indications, number of sessions, number punctures, echosonographic studies for gestational age, placental insertion, punction site, amniotic fluid volume, blood contamination, failures and handling of the patient. A low incidence of abortion is reported. We don't have cases of dripping of amniotic fluid or transvaginal haemorrhage. Multiple insertion of the needle and placental or vessel lesions of the cord, as causes of a fetal death are still argued if we have in mind avoiding chances; we didn't have those complications in our cases. The percent is low if there are not previous spontaneous abortions. 79% of the amniotic fluid samples were sent between the 15th and 17th weeks of pregnancy. For alpha fetus protein determination 12 and for biochemical studies 1, specially for beta-galactosidase level. This was done at the Biomedical Investigation Institute of the National Autonomous University of Mexico (in parents with generalized gangliosidosis GM1). Even though results were good, the technique has still risks and complications. An ultrasonic study of the procedures made by physicians with trustable experience is needed. Our country has the need to create more Prenatal Genetic Diagnosis Centers.

Adult↗