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Biomedical subjects

J Q Chen

Publications and source records attributed to J Q Chen.

At least 73 records · Page 4Linked to original sources

[Infections in the early postoperative period following keratoplasty--a report of seven cases].

Keratoplasty was performed on 3482 eyes from 1965 to 1986 in our hospital. Five eyes (0.14%) were infected in the early postoperative period. Two eyes had endophthalmitis. These seven eyes were operated on again and with local and systemic antibiotics treated as well. Followed up for 36 days to 7 years, six eyes remained safe (5 eyes transparent and 1 eye semi-transparent.) The visual acuity reached 0.3 in two eyes, 0.2 in one eye and finger counting to 0.1 in three eyes. The seventh eye was enucleated because of serious infection. Several factors of infection in the early postoperative period following keratoplasty, causative organisms, the relations between the types of operation in the early postoperative period following keratoplasty were also discussed.

Adolescent↗

[Cross correlation function of BAEP for objective assessment of hearing threshold].

Brainstem auditory evoked potentials (BAEP) recorded were equally divided into two subensembles and a cross correlation function R (lambda) was calculated for them. The average amplitude of R (lambda) around lambda = 0 was chosen as the criterion for hearing threshold measurement. A linear regression equation which represented the relationship between the criterion and stimulus intensity above threshold was obtained on 21 normal and abnormal ears and thus a equation for assessment of hearing threshold was derived. When the equation was applied to ears to be evaluated, the criteria obtained at three different stimulus intensities above threshold were put into the equation and the mean value was calculated for assessment of hearing threshold. The results from 8 ears with different degrees of hearing loss demonstrated that the differences between estimated thresholds and corresponding subjective thresholds are 4.6 dB on the average.

Auditory Threshold↗

A computer-assisted study of quantitative morphological features of C type horizontal cells in retina.

Biphasic C type horizontal cells of the retina of crucian carp were intracellularly stained with horseradish peroxidase (HRP) and quantitatively studied with computer-aided three-dimensional reconstruction techniques. Several parameters characterizing their morphology were determined and compared among different subtypes of horizontal cells. The results show that both cell body area and horizontal extension are proper parameters by which different subtypes of biphasic horizontal cells can be clearly classified.

Animals↗

[Indication of radical surgery (R2, R3) based upon the pattern of lymph node metastasis from gastric cancer].

From Jan. 1980 to June. 1984, radical operation was performed in 156 patients with gastric cancer according to the "protocol" introduced by the Gastric Cancer Research Society of Japan. There were 24 early and 132 advanced gastric cancers. Seventy patients were treated by type R2, 86 by R+2 and R3. Radical distal subtotal gastrectomy was done in 116, proximal subtotal gastrectomy in 7, simple total gastrectomy in 13 and subtotal or total gastrectomy combined with neighbouring organ resection in 20. According to TNM staging, 24 (15.4%) lesions were stage I, 9 (5.8%) stage II, 100 (64.1%) stage III and 23 (14.7%) stage IV. Twenty four lesions were within the mucosa or submucosal layer, 11 in proprius muscle layer, 18 to subserosa, 15 to serosa, 46 beyond serosa, 42 involving the surrounding organs. Lymph node metastatic rate was 66% (103 cases), metastatic degree was 21.5% (558/2593). The metastatic degree of lymph node line I, II and III was 24.7%, 20% and 8.3%, respectively. Basing on lymph node metastatic rate and degree as well as the line degree, it is proposed that, in the early stage of gastric cancer, type R1 be performed for cancer limited to the mucosa, especially the minute type, R2 for cancer invading the submucosa, in which, R+2 be indicated for some isolated patients. In the advanced gastric cancer, type R+2 be performed in the majority of patients and R3 in a few. R3 or total gastrectomy combined with neighbouring organ resection be carried out only in a part of cases with the limited type infiltrating beyond the serosa or invading the neighbouring organs.

Gastrectomy↗

[Pathologic characteristics and the rational surgical treatment of rectal carcinoma].

122 cases with rectal carcinoma were operated by radical resection. The 5 year survival rate was 60.3%. The patho-biological characters of the rectal carcinoma were studied. The results showed that the prognosis of the rectal carcinoma was much better than that of gastric carcinoma due to the fact that most of the rectal carcinoma was localized with low metastatic rate to the lymphatics and its growth patterns are pushing and nest-like. For rational surgical treatment, it is necessary to have a clear understanding of the patho-biologic characters, staging and location of the rectal carcinoma preoperatively.

Adolescent↗