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Biomedical subjects

J Prats

Publications and source records attributed to J Prats.

At least 37 records · Page 2Linked to original sources
PubMed1989

Orbital metastasis, by transitional cell carcinoma of the bladder.

We report a new case of a patient with transitional cell carcinoma of the urinary bladder and a solitary metastasis to the orbita. A review of the literature shows two cases described previously. This case is interesting for the clinical features and evolution.

Carcinoma, Transitional Cell↗
PubMed1980

Management of primary testicular tumors in children.

Between 1966 and 1977, 16 primary testicular tumors (PTT) were treated at the Social Security Children's Hospital in Barcelona. Treatment consisted of resection of the testis, vas deferens and spermatic vessels followed, when the peroperatory biopsy revealed malignancy, by para-aortic lymphadenectomy in 11 of the 13 patients with primary malignant testicular tumors (PMTT). Retroperitoneal radiation therapy was given to patients with positive paraaortic nodes. Chemotherapy was given to all patients with the PMTT. 77.0% of the thirteen patients with PMTT are alive from 1 to 11 yr after surgery. 81.3% of the 16 patients with 13 malignant and 3 benign tumors are alive.

Child↗
PubMed1976

[Testicular tumours in infancy (author's transl)].

Eleven tumours of the testis are presented. Treatment is based in: surgery (gonadectomie and paraaortical lymphadenectomie), quimiotherapy, depending of its pathological pattern and in some cases radiotherapy. In methastasis, surgery if it is possible and poliquimiotherapy. Total mortality rate is 22% (2/11). The follow up is from two to seven years.

Adenocarcinoma↗
PubMedDate not supplied

Improving survival of medulloblastoma: results in two groups of patients.

This retrospective study compares the results obtained in 56 children with medulloblastoma treated with two different protocols at our center between 1975 and 1990. Since 1985 we have been enrolled in the medulloblastoma SIOP II protocol in which we have entered 27 patients. These patients from the SIOP group (SG) and the 29 children treated before 1985, the historical group (HG). When the two groups were compared for age and sex distribution, no differences were found; however, prognostic factors were worse in the HG than in SG: 21 versus 15 T3-T4 and 13 versus 8 high-risk, respectively. The relapse rate was 63% for the HG and 39% for the SG. Five-year disease-free survival was 31% for the HG and 56% for the SG (p = 0.037). Five-year survival was 52 and 70%, respectively (p = 0.055). When SG and HG were compared by stratifying for tumor size, surgical resection and the risk variable, better disease-free survival was obtained in SG than in HG. In a multivariate analysis, the HG and the high-risk proved to be variable independent predictors of poor survival. We observe an increase in survival in our patients with medulloblastoma.

Brain Neoplasms↗
PubMedDate not supplied

[Systemic amyloidosis secondary to xanthogranulomatous pyelonephritis].

Secondary amyloidosis is a relatively common pathology in which chronic infectious diseases are common causes, especially infected bronchiectasis, osteomyelitis or chronic ulcers. The association of xanthogranulomatous pyelonephritis and systemic amyloidosis is extremely rare. To our knowledge, despite innumerable cases of xanthogranulomatous pyelonephritis reported in the literature, this association has been reported in only 8 previous cases. Patients usually complain of fever, back or flank pain and urinary tract symptoms. A long lasting evolution of the process is frequent. We report a 70 year old patient who developed amyloidosis secondary to xanthogranulomatous pyelonephritis. As well as the rarity of this association, this case is exceptional in its clinical presentation, without any urinary tract symptoms that could suggest the diagnosis.

Aged↗
PubMedDate not supplied

Neuroblastoma and transfer factor.

Some authors have demonstrated the cytotoxic capacity of the mother's lymphocytes against the neuroblastoma cells of the son. It is not known if that is the reason for the better prognosis of these tumors in early infancy, and it was decided to treat some similar patients with transfer factor from the mother. The conditions for the patients were: more than 2 years old, poor response to chemotherapy and/or part of the tumor not resected. 3 to 5 doses of transfer factor were administered to 3 patients 2 1/2, 4 and 6 years old. One dose was taken from 400 ml of blood and prepared as described in the literature. The patients remained without metastasis more than 1 year after the treatment.

Child↗