Search PubMed⌕ Search

Biomedical subjects

J Pourel

Publications and source records attributed to J Pourel.

123 records · Page 7Linked to original sources
PubMedDate not supplied

Influence of sulfasalazine on established collagen arthritis in rats.

Collagen induced arthritis (CIA) in rats is an experimental model that is characterized by an erosive synovitis associated with periostitis and both peripheral and axial ossifying enthesopathy. The influence of long-term therapy with sulfasalazine (80 mg/day on weekdays) on established CIA in Wistar Furth rats was investigated. Clinical and X-ray examination showed a significant improvement in the joint lesions of the uninjected paws in the treated rats as compared to controls. This effect was, however, delayed. On the other hand, periosteal new bone formation and caudal enthesopathy (spondylodiscitis) were not altered by the treatment.

Animals↗
PubMedDate not supplied

[Extraskeletal uptake in bone scintigraphy].

Interpretation of a bone scan requires perfect knowledge not only of normal appearances and of the various methods of expression of bony lesions but also of normal or pathological extra-skeletal uptakes which can : (1) be a source of interpretation owing to their superposition with a bony segment. (2) provide useful further information directly linked to the bony disorder studied. (3) permits the unexpected discovery of lesions of the soft tissues. A careful clinical examination of the patient, and knowledge of the whole of the history permits one to explain most of the scanning abnormalities observed.

Bone and Bones↗