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Biomedical subjects

J Pomeroy

Publications and source records attributed to J Pomeroy.

10 recordsLinked to original sources
PubMed1986

Caesarean section as a risk factor for malformations--a negative finding.

The question whether Caesarean section is a risk factor for malformations was examined among 35,865 children born in 1959-65 and included in the US Collaborative Perinatal Project; 1,407 children were subsequent children of mothers who had a Caesarean section for the previous birth (exposed). The rate of malformed children was about the same in the exposed and non-exposed groups, and the rate of children with major malformations was only slightly higher in the exposed group (risk ratio was 1.1, ie not statistically significant). Multiple variable adjustment for potentially confounding factors further reduced the risk ratios. Caesarean section did not appear to be a risk factor in this population, but further studies covering more recent times and including fetal deaths are needed.

Cesarean Section↗
PubMed1985

Acute glomerulonephritis in children. An evolutive morphologic and immunologic study of the glomerular inflammation.

This study deals with 80 children showing a clinically typical acute nephritic syndrome with proteinuria and/or hematuria, edema, and hypertension. Their ages ranged between 2 years 5 months and 16 years; 36 cases were female. In 73 cases a streptococcal infection was demonstrated; the remaining 7 cases did not show morphologic differences with the former. No previous renal disease nor familial history of nephropathies were elicited. In every case a renal biopsy was obtained in the first 60 days of clinical disease; in 46 cases a second renal biopsy was obtained sometime between 6 and 45 months since the beginning of the disease. In 3 cases the renal tissue was considered to be normal by light microscopy, immunofluorescence and electron microscopy in both the first and second biopsies. These 3 patients were not considered as cases of morphologic acute glomerulonephritis in spite of showing a typical clinical picture and they are not included in the evaluation of the glomerular inflammatory evolution. In all the remaining 77 cases C3 granular and segmentary intramembranous and mesangial dense deposits were found in the first biopsy. The second biopsy showed morphologic and immunologic normalization in 27% of the cases, slight lesions in 56% and an increase in severity in 17% of the cases.

Acute Disease↗
PubMed1985

[Historical development, current status and future perspectives of medical education in Chile].

This paper is a critical review in three parts. The first part reviews the past development of medical education in Chile in five stages (1833-1883, 1883-1933, 1933-1968, 1968-1973, and from 1973 to the present), in which the salient features and events are cited. The second part describes the present status of the five medical education programs; undergraduate medical training, graduate medical training, research, advanced training of teaching personnel, and planning and administration. The third part considers the prospects of medical education in each of those five programs. In this part the author presents his conclusions, for example, that it is necessary to review the number of vacancies for admission to the schools of medicine and to measure the academic and vocational aptitude of applicants; that the basic objectives of graduate training should be studied and formulated; that new course subjects should be added in response to the demands that will confront graduates in the future; that the objectives in areas of specialization should be revised; that it is urgent to assess the relationship of research to medical instruction; that pedagogical aspects should be incorporated into the advanced technical training of professionals, and, lastly, that the process of university planning in Chile needs to be refined.

Chile↗
PubMed1975

[Quality control of testosterone and digoxin radioimmunoassays and cortisol competitive protein binding assay by the reference sample method].

The inclusion of a minimum of 2 reference samples in the radioimmunoassay of testesterone and digoxin, and the competitive protein binding assay of cortisol served as a simple and practical index of overall assay performance. Statistical parameters, the mean plus or minus 2 standard deviation limits as well as the % coefficient of variation were determined at 3 clinically significant values for these samples. While a 50% intercept served mainly to indicate standard curve sensitivity, quality control sera provided a valid assessment of annay precision.

Binding, Competitive↗
PubMed1970

Hydroxylysinuria.

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Adolescent↗